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Human Bone Morphogenetic Protein 10 - BMP10 ELISA Kit

BHE12103781

Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.

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Gene ID 27302
UniProt ID O95393
Antigen BMP10
Research Area Signal Transduction; Cardiovascular
Protocol These standard curves of E2241Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration O.D. Average Corrected
2400ng/L 2.127 2.115 2.075
2.103
1200ng/L 1.569 1.451 1.411
1.332
600ng/L 0.72 0.737 0.697
0.753
300ng/L 0.44 0.446 0.406
0.453
150ng/L 0.18 0.156 0.116
0.132
0ng/L 0.049 0.04 0
0.031
Precision We measured random samples of E2241Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay Sample n Mean Standard Deviation CV%
Intra-Assay 1 18 344.37 15.97 4.64
Intra-Assay 2 18 940.91 52.1 5.54
Intra-Assay 3 18 1566.12 66.27 4.23
Storage 2-8°C
SKU Supplier No. Size Your price Quantity
BHE12103781 E2241Hu 48T $320
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BHE12103781 E2241Hu 96T $458
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