Human Atp-sensitive Inward Rectifier Potassium Channel 8

Mfr.No.

E1101Hu

Alternative Names

ATP-sensitive inward rectifier potassium Channel 8;Inward rectifier K(+ Channel Kir6.1;KCNJ8;KIR6.1;Potassium Channel, inwardly rectifying subfamily J member 8;uKATP-1

Reactivity

Human

Detection Range

20-3800ng/L

Sample Type

Serum, Plasma, Cell culture supernatants

Assay Type

Sandwich

Assay Duration

1h 30m

Molecular Weight

47968

Kit Components

Components	Quantity
Pre-coated ELISA plate	12 * 8 well strips x1
Standard solution	0.5ml x1
Standard diluent	3ml x1
Streptavidin-HRP	6ml x1
Stop solution	6ml x1
Substrate solution A	6ml x1
Substrate solution B	6ml x1
Wash buffer concentrate (25x)	20ml x1
Biotinylated antibody	1ml x1

Sensitivity

10.14ng/L

Background

This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium (By similarity).

Gene ID	3764
UniProt ID	Q15842
Antigen	KCNJ8

Research Area

Neuroscience

Protocol

These standard curves of E1101Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration	O.D.	Average	Corrected
2000ng/L	2.133	2.186	2.136
	2.239
1000ng/L	1.364	1.425	1.375
	1.486
500ng/L	0.916	0.861	0.81
	0.806
250ng/L	0.438	0.469	0.418
	0.499
125ng/L	0.23	0.257	0.207
	0.285
0ng/L	0.042	0.051	0
	0.059

Precision

We measured random samples of E1101Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay	Sample	n	Mean	Standard Deviation	CV%
Intra-Assay	1	18	662.03	35.75	5.4
Intra-Assay	2	18	1035.02	36.16	3.49
Intra-Assay	3	18	262.21	16.01	6.1

Storage	2-8°C

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SKU	Supplier No.	Size	Your price	Quantity
BHE12102751	E1101Hu	48T	$320		Add to Cart
BHE12102751	E1101Hu	96T	$458		Add to Cart

Human Atp-sensitive Inward Rectifier Potassium Channel 8 - KCNJ8 ELISA Kit

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