[Isoform 1]: Water Channel that mediates water transport across cell membranes irrespective of the cytosolic pH (PubMed: 1208$458.00|$300.001, PubMed: 21733844, PubMed: 23382902, PubMed: 30420639). The Channel is permeable to glycerol, especially when the cytosolic pH is acidified (PubMed: 21733844, PubMed: 30420639). Contributes to adipocyte water and glycerol permeability, and may thereby contribute to the utilization of glycerol derived from phospholipid degradation (PubMed: 23382902). May contribute to water transport in the intestine (Probable). [Isoform 2]: Water Channel that mediates water transport across cell membranes, but that is not permeable to glycerol.
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