Human Abnormal Spindle-like Microcephaly-associated Protein

Mfr.No.

E4890Hu

Alternative Names

Abnormal spindle protein homolog;Abnormal spindle-like microcephaly-associated protein;Asp homolog;ASPM

Reactivity

Human

Detection Range

15-3000ng/L

Sample Type

Serum, Plasma, Cell culture supernatants

Assay Type

Sandwich

Assay Duration

1h 30m

Molecular Weight

409800

Kit Components

Components	Quantity
Pre-coated ELISA Plate	12 * 8 well strips x1
Standard solution	0.5ml x1
Standard diluent	3ml x1
Streptavidin-HRP	6ml x1
Stop solution	6ml x1
Substrate solution A	6ml x1
Substrate solution B	6ml x1
Wash buffer concentrate (25x)	20ml x1
Biotinylated antibody	1ml x1

Sensitivity

7.35ng/L

Background

Involved in mitotic spindle regulation and coordination of mitotic processes. The function in regulating microtubule dynamics at spindle poles including spindle orientation, astral microtubule density and poleward microtubule flux seems to depend on the association with the katanin complex formed by KATNA1 and KATNB1. Enhances the microtubule lattice severing activity of KATNA1 by recruiting the katanin complex to microtubules. Can block microtubule minus-end growth and reversely this function can be enhanced by the katanin complex (PubMed: 28436967). May have a preferential role in regulating neurogenesis.

Gene ID	259266
UniProt ID	Q8IZT6
Antigen	ASPM

Research Area

Others

Protocol

These standard curves of E4890Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration	O.D.	Average	Corrected
1600ng/L	2.364	2.312	2.265
	2.259
800ng/L	1.834	1.779	1.732
	1.725
400ng/L	1.219	1.243	1.196
	1.267
200ng/L	0.614	0.626	0.579
	0.639
100ng/L	0.428	0.391	0.345
	0.355
0ng/L	0.046	0.047	0
	0.048

Precision

We measured random samples of E4890Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay	Sample	n	Mean	Standard Deviation	CV%
Intra-Assay	1	18	304.2	18.04	5.9
Intra-Assay	2	18	661.9	39.12	5.9
Intra-Assay	3	18	198.7	12.69	6.4

Storage	2-8°C

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SKU	Supplier No.	Size	Your price	Quantity
BHE12106163	E4890Hu	48T	$320		Add to Cart
BHE12106163	E4890Hu	96T	$458		Add to Cart

Human Abnormal Spindle-like Microcephaly-associated Protein - ASPM ELISA Kit

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