Model Description: Exon 2 of Dbt gene was deleted to generate Dbt knockout mice.
Official Symbol: Dbt
NCBI ID: 13171
MGI ID: 105386
Ensembl ID: ENSMUSG00000000340
Pubmed: Dbt
Human Ortholog: DBT
Nomenclature
C57BL/6JSmoc-Dbtem1Smoc
Exon
Exon 2
Application
Studies On Degradation And Metabolism Of Valine, Leucine And Isoleucine
Disease
Maple Syrup Urine Disease
Disease
Rare Disease
KI/KO Gene
Dbt
Synonyms
BCKAD-E2, D3Wsu60e
Reference
Homanics GE, Skvorak K, Ferguson C, Watkins S, Paul HS, Production and characterization of murine models of classic and intermediate maple syrup urine disease. BMC Med Genet. 2006;7:33