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Home / Primary Antibodies / Conjugated Primary Antibodies

NR1H2 Antibody, FITC conjugated

SKU : BHA10521474

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA016045HC01HU
Alternative Names	Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear receptor NER) (Nuclear receptor subfamily 1 group H member 2) (Ubiquitously-expressed nuclear receptor), NR1H2, LXRB NER UNR
Categories	Primary Antibodies
Clonality	polyclonal
Description	Nuclear receptor. Binds preferentially to double-stranded oligonucleotide direct repeats having the consensus half-site sequence 5'-AGGTCA-3' and 4-nt spacing (DR-4). Regulates cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8; DLDLR and LRP8. Interplays functionally with RORA for the regulation of genes involved in liver metabolism (By similarity). Exhibits a ligand-dependent transcriptional activation activity (PubMed:25661920).
Host	Rabbit
Immunogen	Recombinant Human Oxysterols receptor LXR-beta protein (1-461AA)
Isotype	IgG
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Nuclear receptor. Binds preferentially to double-stranded oligonucleotide direct repeats having the consensus half-site sequence 5'-AGGTCA-3' and 4-nt spacing (DR-4). Regulates cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8; DLDLR and LRP8. Interplays functionally with RORA for the regulation of genes involved in liver metabolism (By similarity). Exhibits a ligand-dependent transcriptional activation activity (PubMed:25661920).
Species	Homo Sapiens (Human)
Subcellular Location	Nucleus

Uniprot	P55055
Database Links	HGNC:7965 OMIM:600380 KEGG:hsa:7376 STRING:9606.ENSP00000253727 UniGene:Hs.432976
Function	Nuclear receptor. Binds preferentially to double-stranded oligonucleotide direct repeats having the consensus half-site sequence 5'-AGGTCA-3' and 4-nt spacing (DR-4). Regulates cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8; DLDLR and LRP8. Interplays functionally with RORA for the regulation of genes involved in liver metabolism (By similarity). Exhibits a ligand-dependent transcriptional activation activity
Protein Families	Nuclear hormone receptor family, NR1 subfamily
Research Area	Cardiovascular
Tissue Specificity	Ubiquitous.

Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form	Liquid
Format	Liquid
Purification	>95%, Protein G purified
Purity	>95%,Protein G purified
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Applications	ELISA
Description	ELISA
Tested Application	ELISA

Datasheet
ELISA Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10521474	CSB-PA016045HC01HU	100ug	$299		Add to Cart
BHA10521474	CSB-PA016045HC01HU	50ug	$166		Add to Cart

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