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Home / Primary Antibodies / Conjugated Primary Antibodies

anti-human CD357(GITR)

SKU : BHA14700153

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Ancell Corporation

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Mfr.No.	368, 368-020, 368-030, 368-040, 368-050, 368-820
Alternative Names	GITR, AITR, anti-AITR, glucocorticoid induced tumor necrosis, anti-GITR factor, TNFRSF18
Background	Glucocorticoid induced Tumor Necrosis Factor receptor family related gene (GITR, AITR) is a type 1 228 amino acid transmembrane protein that has been designated TNFRSF18. GITR is expressed mainly byCD4+ CD25+ T lymphocytes. Its engagement by antibodies or its ligand (GITRL) induces a costimulatory signal which can break T cell suppression (2). GITR has been implicated as a regulatory mechanism in anti-parasitic immune responses (4), and is involved with Macrophages activation in atherosclerotic plaque formation (3). Clone ANC5A3 binds to human GITR in EIA and on stimulated cell surface in FACS. Preincubation of the receptor with an excess of this mAb will block binding of recombinant GITR Ligand.
Formulation	50 mM Sodium Phosphate pH 7.5, 500 mM Potassium Chloride, 150mM NaCl, 0.5% Gentamicin sulfate
Isotype	IgG3k
Reactivity	Human
Specificity	human

Storage Buffer	50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 0.5 mg/ml Gentamicin Sulfate (as a preservative).

Applications	EIA, FC

Product Manual	Data Sheet

No Description Available.

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Combination SKU	Supplier No.	Conjugate	Size	Your price	Quantity
BHA14700153-1	368-020	Pur WA	100 ug	$235		Add to Cart
BHA14700153-2	368-030	Biotin	100 ug	$325		Add to Cart
BHA14700153-3	368-040	FITC	120 tests	$325		Add to Cart
BHA14700153-4	368-050	PE	120 tests	$350		Add to Cart
BHA14700153-5	368-820	Pur/PF	100 ug	$235		Add to Cart

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