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Home / Primary Antibodies / Conjugated Primary Antibodies

anti-human CD244(2B4)

SKU : BHA14700099

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Ancell Corporation

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Mfr.No.	259, 259-020, 259-040, 259-820
Alternative Names	2B4
Background	CD244 (2B4, SLAMF4) is a 66 kD member of the CD2/SLAM related receptor family (SRR). It is expressed on NK (3), Tcell subsets, monocytes and eosinophils(4). It is expressed at high levels on Leuikemia initiating cells, and plays a role in their proliferative potential (5). In mice there are two transcription variants, a long form and a short form of CD244 each of which have distinct signaling properties. In humans, only the long form is expressed. Decreased CD244 expression on monocytes of SLE patients correlated (negatively) with autoantibody titer(2). CD244 mediated function in immune response can vary greatly dependant on the context of its ligation. Antibody ANC2B4/3B12 binds to recombinant CD244-muIg (cat #544-020) in EIA, and to cell surface CD244 on human PBL in FACS. ANC2B4/3B12 binds to a CD244 epitope that is distinct from the binding sites of clone ANC244.8 (cat #239-020) and clone C1.7.
Formulation	50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 0.5% Gentamicin sulfate
Host	CHO cells
Isotype	IgG1k
Reactivity	Human
Specificity	human

Purity	Antibody was Protein A purified from (low FBS containing) tissue culture supernatant. Purity was >95% Immunoglobulin by SDS-PAGE and contains less than 1% Bovine Immunoglobulin. Product was 0.2 um filtered and vialed under aseptic conditions.
Storage	Store at 2 - 5°C. Freeze/Thawing is not recommended.
Storage Buffer	50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 0.5 mg/ml Gentamicin Sulfate (as a preservative).

Applications	EIA, FC

Product Manual	Data Sheet

No Description Available.

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Combination SKU	Supplier No.	Conjugate	Size	Your price	Quantity
BHA14700099-1	259-020	Pur WA	100 ug	$235		Add to Cart
BHA14700099-2	259-040	FITC	120 tests	$325		Add to Cart
BHA14700099-3	259-820	Pur/PF	100 ug	$235		Add to Cart

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