HIST1H2AG (Ab-119) Antibody

Mfr.No.	CSB-PA010389PA119ncrHU
Alternative Names	Histone H2A type 1 (H2A.1) (Histone H2A/ptl), HIST1H2AG; HIST1H2AI; HIST1H2AK; HIST1H2AL; HIST1H2AM, H2AFP; H2AFC; H2AFD; H2AFI; H2AFN
Categories	Primary Antibodies
Clonality	polyclonal
Description	Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Host	Rabbit
Immunogen	Peptide sequence around site of Lys (119) derived from Human Histone H2A type 1.
Isotype	IgG
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Species	Homo Sapiens (Human)
Subcellular Location	Nucleus, Chromosome

Uniprot	P0C0S8
Gene Id	8329
Database Links	HGNC:4737 OMIM:602787 KEGG:hsa:8329 STRING:9606.ENSP00000352627 UniGene:Hs.134999
Function	Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Protein Families	Histone H2A family
Research Area	Epigenetics and Nuclear Signaling
Weight	14,091 Da

Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form	Liquid
Format	Liquid
Purification	Antigen Affinity Purified
Purity	Antigen Affinity Purified
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Applications

ELISA, IHC, ChIP

Description

ELISA ; IHC ; ChIP, IF ; ELISA ; ChIP ; IHC

Dilution

IHC	1:20-1:200

Tested Application

ELISA, IHC, IF, ChIP; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Datasheet
ELISA Protocol
Immunohistochemistry (IHC) Protocol
Native Chromatin Immunoprecipitation(ChIP) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10532031	CSB-PA010389PA119ncrHU	100ul	$319		Add to Cart
BHA10532031	CSB-PA010389PA119ncrHU	50ul	$175		Add to Cart