HIST1H1E (Ab-25) Antibody

Mfr.No.	CSB-PA010380PA25nme1HU
Alternative Names	Histone H1.4 (Histone H1b) (Histone H1s-4), HIST1H1E, H1F4
Categories	Primary Antibodies
Clonality	polyclonal
Description	Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity).
Host	Rabbit
Immunogen	Peptide sequence around site of Lys (25) derived from Human Histone H1.4.
Involvement In Disease	Rahman syndrome (RMNS)
Isotype	IgG
Raised In	Rabbit
Reactivity	Human, Mouse
Regulatory	RUO
Relevance	Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity).
Species	Homo Sapiens (Human)
Subcellular Location	Nucleus, Chromosome

Uniprot	P10412
Gene Id	3008
Database Links	HGNC:4718 OMIM:142220 KEGG:hsa:3008 STRING:9606.ENSP00000307705 UniGene:Hs.248133
Function	Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity).
Protein Families	Histone H1/H5 family
Research Area	Epigenetics and Nuclear Signaling
Weight	21,865 Da

Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form	Liquid
Format	Liquid
Purification	Antigen Affinity Purified
Purity	Antigen Affinity Purified
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4