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IL-2 Luciferase Reporter Jurkat cell line

SKU : BHC18200011

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BPS Bioscience

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Mfr.No.	60481
Description	Human IL-2 reporter construct is stably integrated into the genome of Jurkat T-cells. The firefly luciferase gene is controlled by a human IL-2 promoter. Mycoplasma testing: This cell line has been screened using the MycoAlert Mycoplasma Detection Kit (Cat. No. LT07-118) to confirm the absence of Mycoplasma contamination. MycoAlert Assay Control Set (Cat. No. LT07-518) was used as a positive control. Host Species: human
Background	Interleukin-2 (IL-2) is a key cytokine important for proliferation and differentiation of T cells into effector T cells through interaction with the IL-2 receptor.
Application	The IL-2-luciferase Jurkat reporter cell line is suitable for monitoring the transcription activity of IL-2 in response to stimulants, and establishing cell-based screens for inhibitors that target specific IL-2 stimulating molecules.
Host Cell	Jurkat
Synonyms	IL2 Cell Line IL2 bioassay IL-2
Shipping Temperature	-80°C (dry ice)
Note	License Disclosure:Purchase of this cell line grants you with a 10-year license to use this cell line in your immediate laboratory, for research use only. This license does not permit you to share, distribute, sell, sublicense, or otherwise make the cell line available for use to other laboratories, departments, research institutions, hospitals, universities, or biotech companies. The license does not permit use of this cell line in humans or for therapeutic or drug use. The license does not permit modification of the cell line in any way. Inappropriate use or distribution of this cell line will result in revocation of the license and result in an immediate cease of sales and distribution of Biohippo products to your laboratory. Biohippo does not warrant the suitability of the cell line for any particular use, and does not accept any liability in connection with the handling or use of the cell line. Modifications of this cell line, transfer to another facility, or commercial use of the cells may require a separate license and additional fees; contact orders@biohippo.com for details. Publications using this cell line should reference Biohippo Inc. Warning: Avoid freeze/thaw cycles.

Product Format	Each vial contains ~2 x 10^6 cells in 1 ml of 10% DMSO in FBS.
Storage Stability	Store in liquid nitrogen immediately upon receipt.

Reference	1. Weaver JR et.al. (2007) Characterization of the sequence and architectural constraints of the regulatory and core regions of the human interleukin-2 promoter. Mol. Immunol. 44: 2813-2819.2. Hughes CCW and Pober JS (1996) Transcriptional Regulation of the Interleukin-2 Gene in Normal Human Peripheral Blood T Cells. J. Biol. Chem. 271: 5369-5377.

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SKU	Supplier No.	Size	Your price	Quantity
BHC18200011	60481	2 vials	$7562.50		Add to Cart

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