Cells isolated from cord blood containing lower MHC Class II molecules are programmed using our patented virus-free method using episomal DNA and our proprietary mix of vectors, excluding l-Myc, c-Myc, and Lin28 transcription factors.
The cell line was validated for pluripotency based on colony morphology, alkaline phosphatase expression, and expression of SSEA-4. Cells are free of Mycoplasma and exhibit classical morphology and growth characteristics.
Multipotent stem cells can self-renew through dividing and can be developed into multiple specific cell types for a particular tissue tropism. These cells can be differentiated into all cell types within one lineage for cell therapy, regenerative medicine, and fertility applications.