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Disease Mice

Disease Mice

Mouse models are very useful because they share mammalian features with humans and suffer from many of the same diseases. Many mouse models have been created to target specific human diseases using genetic engineering.

  • Trp53-flox-R172H

    Trp53-flox-R172H

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tr
    • Application : Spontaneous Tum
    • KI/KO Gene : Trp53
    • Synonyms : bbl; bfy; bhy;
  • Tyro3-KO

    Tyro3-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ty
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Autoimmune Dise
  • Ifnar1-KO

    Ifnar1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-If
    • Exon : Exon 3-11
    • Application : Immune System
    • Disease : Autoimmune Dise
  • hOCLN

    hOCLN

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Oc
    • Exon : Exon 3-11
    • Application : Hcv Infection R
    • Disease : Autoimmune Dise
  • H11-pAlb-NTCP-C9-IRES-EGFP

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ig
    • Exon : Exon 3-11
    • Application : Hbv And Hdv Inf
    • Disease : Autoimmune Dise
  • Akt1-KO

    Akt1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ak
    • Exon : Exon 2
    • Application : Pro-Inflammator
    • Disease : Schizophrenia
  • Angptl6-KO

    Angptl6-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-An
    • Exon : Exon 3
    • Application : Pro-Inflammator
    • Disease : Obesity
  • Avpr1a-KO

    Avpr1a-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Av
    • Exon : Exon 1-2
    • Application : Therapeutic Ant
    • Disease : Schizophrenia
  • Arx-Flox

    Arx-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ar
    • Exon : Exon s
    • Application : Therapeutic Ant
    • Disease : Early Infantile
  • Arg1-KO

    Arg1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ar
    • Exon : Exon 3
    • Application : Innate Immune S
    • Disease : Hyperargininemi
  • Ar-Flox

    Ar-Flox

    • Description : Model Descripti
    • Nomenclature : B6;129S-Artm1(f
    • Exon : Exon 2
    • Application : Innate Immune S
    • Disease : Prostate Cancer
  • Btd-KO

    Btd-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Bt
    • Exon : Exon 2-3
    • Application : Metabolism And
    • Disease : Biotinidase Def
  • Bmp1-Flox

    Bmp1-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Bm
    • Exon : Exon 3-6
    • Application : Research On Lip
    • Disease : Osteogenesis Im
  • Cdkal1-Flox

    Cdkal1-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cd
    • Exon : Exon s
    • Application : Research On Lip
    • Disease : Type 2 Diabetes
  • CAG-hACE2-IRES-Luc-Tg

    CAG-hACE2-IRES-Luc-Tg

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tg
    • Exon : Exon s
    • Application : Corona Virus Re
    • Disease : Type 2 Diabetes
  • Cox7a1-KO

    Cox7a1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Co
    • Exon : Exon 2-3
    • Application : Corona Virus Re
    • Disease : Dilated Cardiom
  • Chrnb2-KO

    Chrnb2-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ch
    • Exon : Exon 2
    • Application : Corona Virus Re
    • Disease : Autism Spectrum
  • Chd8-KO

    Chd8-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ch
    • Exon : Exon 2-3
    • Application : Corona Virus Re
    • Disease : Autism Spectrum
  • Dag1-Flox

    Dag1-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Da
    • Exon : Exon 4
    • Application : Corona Virus Re
    • Disease : Dilated Cardiom
  • Ctsc-KO

    Ctsc-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ct
    • Exon : Exon 2-3
    • Application : Papillon-Lefevr
    • Disease : Schizophrenia
  • Dlgap4-KO

    Dlgap4-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Dl
    • Exon : Exon 4
    • Application : Papillon-Lefevr
    • Disease : Autism Spectrum
  • Disc1-KO

    Disc1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Di
    • Exon : Exon 2
    • Application : Papillon-Lefevr
    • Disease : Schizophrenia
  • Esrrb-Flox

    Esrrb-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Es
    • Exon : Exon s
    • Application : Papillon-Lefevr
    • Disease : Dilated Cardiom
  • Fas-KO(BALB/c)

    Fas-KO(BALB/c)

    • Description : Model Descripti
    • Nomenclature : BALB/cAnSmoc-Fa
    • Exon : Exon 2
    • Application : Immune-Related
    • Disease : Systemic Lupus
  • Fah-KO

    Fah-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Fa
    • Exon : Exon 8
    • Application : Tyrosinemia Typ
    • Disease : Tyrosinemia Typ