Zerumbone

Mfr.No.	SIH-265
Alternative Names	(2E,6E,10E)-2,6,9,9-Tetramethyl-2,6,10-cycloundecatrien-1-one
Appearance	White to off-white solid
Function	NF-κB kinase inhibitor
Inchi	InChI=1S/C15H22O/c1-12-6-5-7-13(2)14(16)9-11-15(3,4)10-8-12/h7-9,11H,5-6,10H2,1-4H3/b11-9+,12-8+,13-7+
Inchikey	GIHNTRQPEMKFKO-SKTNYSRSSA-N
Mode Of Action	Inhibitor
Molecular Formula	C15H22O
Pubchem Cid	5470187
Research Area	Cancer ; Apoptosis
Safety Phrases	Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
Smiles	C/C/1=CCC(/C=C/C(=O)/C(=C/CC1)/C)(C)C
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Cas Number	471-05-6
Molecular Weight	218.3
Scientific Background	Potentiates TRAIL-induced apoptosis via upregulation of death receptor DR4 and DR5 expression. Has no cytotoxic effect on normal cells. Cell permeable. Natural sesquiterpene ketone isolated from Zingiber sp.
Solubility	Soluble in DMSO (≥10 mg/ml)
Source	Synthetic
Adr Code	Non-hazardous
Country Of Origin	Canada
Tarriff Code	3822.00.1090

Reference	1. Leu J.L., et al. (2009) Mol Cell. 36:15.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHB11900087-1	SIH-265-10MG	10 mg	$52		Add to Cart
BHB11900087-2	SIH-265-50MG	50 mg	$215		Add to Cart