Marcfortine A

Mfr.No.	T35745
Description	Marcfortine A is an indole alkaloid originally isolated from P. roqueforti. It has nematocidal activity against the parasitic nematode H. contortus (LD99 = 0.06 ug/ml) and inhibits motility of adult worms (EC50 = 2 uM)., Marcfortine A eliminates H. contortus, T. colubriformis, and O. ostertagi from experimentally infected jirds (ED95s = 0.33, 0.11, and 2.5 mg/animal, respectively). It dose-dependently inhibits nicotine-induced calcium mobilization in SH-SY5Y and TE-671 cells expressing alpha3 subunit-containing human nicotinic acetylcholine receptors (nAChRs) and muscle-type nAChRs, respectively.
Molecular Formula	C28H35N3O4
Signaling Pathways	Others
Smiles	(H)(C)12C(C)34CCCCN3C(C)1(C(C)1(C(=O)Nc3c1ccc1OC(C)(C)C=COc31)C2(C)C)N(C)C4=O \|c:28,:29,THB:29:1:8.9:32.34\|
Cas Number	75731-43-0
Molecular Weight	477.605
Target	Others

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SKU	Supplier No.	Size	Your price	Quantity
BHB20425148	T35745	1 mg	$850		Add to Cart