AS-8351

Mfr.No.	SIH-558
Alternative Names	AS8351, 2-Hydroxy-1-naphthylaldehyde isonicotinoylhydrazone; NSC-51355, N'-[(Z)-(2-oxonaphthalen-1-ylidene)methyl]pyridine-4-carbohydrazide, N'-[(2-oxonaphthalen-1-ylidene)methyl]pyridine-4-carbohydrazide, N'-[(Z)-(2-oxo-1-naphthylidene)methyl]pyridine-4-carbohydrazide, N'-[(2-oxo-1-naphthylidene)methyl]pyridine-4-carbohydrazide, N'-[(Z)-(2-oxo-1-naphthylidene)methyl]-4-pyridinecarbohydrazide, N'-[(2-oxo-1-naphthylidene)methyl]-4-pyridinecarbohydrazide, N'-[(Z)-(2-keto-1-naphthylidene)methyl]isonicotinohydrazide, N'-[(2-keto-1-naphthylidene)methyl]isonicotinohydrazide, 796-42-9, 2-Hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone, NSC51355, NCI60_004242, ZINC00061171, CBDivE_006818, 311 Iron Chelator, 2-Hydroxy-1-naphthaldehyde isonicotinoyl hydrazone
Appearance	Yellow powder
Function	KDM5B histone demethylase inhibitor
Inchi	InChI=1S/C17H13N3O2/c21-16-6-5-12-3-1-2-4-14(12)15(16)11-19-20-17(22)13-7-9-18-10-8-13/h1-11,19H,(H,20,22)/b15-11-
Inchikey	UBECDIQQXGETMR-PTNGSMBKSA-N
Mode Of Action	Inhibitor
Molecular Formula	C17H13N3O2
Pubchem Cid	5353827
Research Area	Stem Cells
Safety Phrases	GHS Classification: Skin irritation (Category 2), H315 Eye irritation (Category 2A), H319 Specific target organ toxicity - single exposure (Category 3), Respiratory system, H335 Signal word: Warning Hazard statement(s): H315 Causes skin irritation. H319 Causes serious eye irritation. H335 May cause respiratory irritation. Precautionary statement(s): P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray. P264 Wash skin thoroughly after handling. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/ eye protection/ face protection. P302 + P352 IF ON SKIN: Wash with plenty of soap and water. P304 + P340 + P312 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P332 + P313 If skin irritation occurs: Get medical advice/ attention. P337 + P313 If eye irritation persists: Get medical advice/ attention. P362 Take off contaminated clothing and wash before reuse. P403 + P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up. P501 Dispose of contents/ container to an approved waste disposal plant.
Smiles	O=C(NNC=C1/C(=O)C=Cc2ccccc12)c3ccncc3
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Cas Number	796-42-9
Molecular Weight	291.3
Solubility	May be dissolved in DMSO (45 mg/ml); or ethanol (10 mg/ml, warm); or DMF (30 mg/ml)
Source	Synthetic
Adr Code	Non-hazardous
Country Of Origin	Canada
Tarriff Code	3822.00.1090

Shipping Temperature	Shipped Ambient
Gross Weight (kg)	0.25
Net Weight (g)	0.005
Purity	>98% (TLC); NMR (Conforms)
Storage Temperature	-20ºC
Stock Product	Y

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHB11900336-1	SIH-558-5MG	5 mg	$90		Add to Cart
BHB11900336-2	SIH-558-25MG	25 mg	$359		Add to Cart

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