(±)16(17)-EpDPA

Mfr.No.	T37235
Description	EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-derived (prostacyclin) vasodilators.(1),(2)Cytochrome P450 (CYP450) metabolism of polyunsaturated fatty acids produces epoxides such as (±)14(15)-EET which are prime candidates for the actual active mediator.(3) However, the CYP450 metabolites of eicosapentaenoic acid and docosahexaenoic acid have been little studied relative to arachidonate epoxygenase metabolites. (±)16(17)-EpDPA is the DHA homolog of (±)14(15)-EpETrE, derived via epoxidation of the 16,17-double bond of DHA. The EDHF activity of (±)16(17)-EpDPA has not yet been determined. The epoxygenase metabolites of DHA have also been detected in a mouse inflammation model.(4)
Alternative Names	(±)16,17 EDP
Molecular Formula	C22H32O3
Signaling Pathways	Others
Smiles	CCC=C/C(CH)1O(CH)1CC=C/CC=C/CC=C/CC=C/CCC(O)=O
Cas Number	155073-46-4
Molecular Weight	344.495
Target	Others

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SKU	Supplier No.	Size	Your price	Quantity
BHB20426414	T37235	1 mg	-		Add to Quote