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Home / Assay Kits / ELISA Kits

ELISA Kit for Rat Transcription factor GATA-4

SKU : BHE13804127

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0374r
Alternative Names	DNA-binding protein GATA-GT2 ; GATA-binding factor 4
Categories	Elisa
Function	Transcriptional activator. Binds to the upstream sequence of the H(+)/K(+)-ATPase beta gene and to a sequence containing the GATA motif. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. Promotes cardiac myocyte enlargement.
Specificity	Natural and recombinant Rat Transcription factor GATA-4
Subcellular Location	Nucleus
Detection Range	0.156-10ng/mL
Entryname	GATA4_RAT
Method Type	Sandwich
Platform	PF00320
Protein Name	Transcription factor GATA-4
Sensitivity	0.091ng/mL
Sequence	50: MYQSLAMAAN ; HGPPPGAYEA ; GGPGAFMHSA ; GAASSPVYVP ; TPRVPSSVLG ; 100: LSYLQGGGSG ; AASGATSGGS ; SGAGPSGAGP ; GTQQGSPGWS ; QAGAEGAAYT ; 150: PPPVSPRFSF ; PGTTGSLAAA ; AAAAAAREAA ; AYSSSGGAAG ; AGLAGREQYG ; 200: RPGFAGSYSS ; PYPAYMADVG ; ASWAAAAAAS ; AGPFDSPVLH ; SLPGRANPAR ; 250: HPNLDMFDDF ; SEGRECVNCG ; AMSTPLWRRD ; GTGHYLCNAC ; GLYHKMNGIN ; 300: RPLIKPQRRL ; SASRRVGLSC ; ANCQTTTTTL ; WRRNAEGEPV ; CNACGLYMKL ; 350: HGVPRPLAMR ; KEGIQTRKRK ; PKNLNKSKTP ; AGPPGESLPP ; SSGASSNSSN ; 400: ATSSSSSSEE ; MRPIKTEPGL ; SSHYGHSSSM ; SQTFSTVSGH ; GSSIHPVLSA ; 440: LKLSPQGYPS ; PVTQTSQASS ; KQDSWNSLVL ; ADSHGDIITA ;
Sequence Length	440
String	P46152
Sub Unit	Interacts with the homeobox domain of NKX2-5 through its C-terminal zinc finger. Also interacts with JARID2 which represses its ability to activate transcription of ANF. Interacts with NFATC4 and LMCD1. Forms a complex made of CDK9, CCNT1/cyclin-T1, EP300 and GATA4 that stimulates hypertrophy in cardiomyocytes (By similarity). Interacts with ZNF260.

Uniprot	P46152
Gene Name	Gata4
Immunogen Species	Rattus norvegicus (Rat)
Kegg	rno:54254
Unigene	Rn.26251

Reference	1. "Gastric DNA-binding proteins recognize upstream sequence motifs of parietal cell-specific genes." Tamura S., Wang X.H., Maeda M., Futai M. Proc. Natl. Acad. Sci. U.S.A.90:10876-10880(1993) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: Wistar. tissue: Stomach. 2. Tamura S., Wang X.H., Maeda M., Futai M. Proc. Natl. Acad. Sci. U.S.A.91:4609-4609(1994) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM 3. "SMAD-mediated modulation of YY1 activity regulates the BMP response and cardiac-specific expression of a GATA4/5/6-dependent chick Nkx2.5 enhancer." Lee K.H., Evans S., Ruan T.Y., Lassar A.B. Development131:4709-4723(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DNA-BINDING 4. "The zinc finger-only protein Zfp260 is a novel cardiac regulator and a nuclear effector of alpha1-adrenergic signaling." Debrus S., Rahbani L., Marttila M., Delorme B., Paradis P., Nemer M. Mol. Cell. Biol.25:8669-8682(2005) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ZNF260

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SKU	Supplier No.	Size	Your price	Quantity
BHE13804127	E0374r	96T	$796		Add to Cart

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