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Home / Assay Kits / ELISA Kits

ELISA Kit for Rat Long-chain fatty acid transport protein 1

SKU : BHE13810023

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E12692r
Alternative Names	Solute carrier family 27 member 1 ; Fatp ; Fatp1
Categories	Elisa
Function	Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. The LFCA import appears to be hormone-regulated in a tissue-specific manner. In adipocytes, but not myocytes, insulin induces a rapid translocation of Fatp1 from intracellular compartments to the plasma membrane, paralleled by increased LFCA uptake. May act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane-associated multimeric protein complex to trap and draw fatty acids towards accumulation. Plays a pivotal role in regulating available LFCA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids.
Specificity	Natural and recombinant Rat Long-chain fatty acid transport protein 1
Subcellular Location	Cell membrane Single-pass membrane protein Endomembrane system Single-pass membrane protein Cytoplasm Plasma membrane and intracellular membranes, at least in adipocytes. Predominantly cytoplasmic in myocytes.
Detection Range	0.312-20ng/mL
Entryname	S27A1_RAT
Method Type	Sandwich
Platform	PF00501
Protein Name	Long-chain fatty acid transport protein 1
Sensitivity	0.168ng/mL
Sequence	50: MRTPGAGTAS ; VASLGLLWLL ; GLPWTWSAAA ; AFGVYVGSGG ; WRFLRIVCKT ; 100: ARRDLFGLSV ; LIRVRLELRR ; HRRAGDTIPR ; IFQAVAQRQP ; ERLALVDASS ; 150: GICWTFAQLD ; TYSNAVANLF ; LQLGFAPGDV ; VAVFLEGRPE ; FVGLWLGLAK ; 200: AGVVAALLNV ; NLRREPLAFC ; LGTSAAKALI ; YGGEMAAAVA ; EVSEQLGKSL ; 250: LKFCSGDLGP ; ESVLPDTQLL ; DPMLAEAPTT ; PLAQAPGKGM ; DDRLFYIYTS ; 300: GTTGLPKAAI ; VVHSRYYRIA ; AFGHHSYSMR ; ANDVLYDCLP ; LYHSAGNIMG ; 350: VGQCIIYGLT ; VVLRKKFSAS ; RFWDDCVKYN ; CTVVQYIGEI ; CRYLLRQPVR ; 400: DVERRHRVRL ; AVGNGLRPAI ; WEEFTQGFGV ; RQIGEFYGAT ; ECNCSIANMD ; 450: GKVGSCGFNS ; RILTHVYPIR ; LVKVNEDTME ; PLRDSQGLCI ; PCQPGEPGLL ; 500: VGQINQQDPL ; RRFDGYVSDS ; ATNKKIAHSV ; FRKGDSAYLS ; GDVLVMDELG ; 550: YMYFRDRSGD ; TFRWRGENVS ; TTEVEAVLSR ; LLGQTDVAVY ; GVAVPGVEGK ; 600: SGMAAIADPH ; NQLDPNSMYQ ; ELQKVLASYA ; QPIFLRLLPQ ; VDTTGTFKIQ ; 646: KTRLQREGFD ; PRQTSDRLFF ; LDLKQGRYLP ; LDERVHARIC ; AGDFSL
Sequence Length	646
String	P97849
Sub Unit	Self-associates. May function as an homodimer.

Uniprot	P97849
Gene Name	Slc27a1
Immunogen Species	Rattus norvegicus (Rat)
Unigene	Rn.1047

Reference	1. "Molecular cloning of fatty acid-transport protein cDNA from rat." Schaap F.G., Hamers L., van der Vusse G.J., Glatz J.F.C. Biochim. Biophys. Acta1354:29-34(1997) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] 2. "The subcellular compartmentation of fatty acid transporters is regulated differently by insulin and by AICAR." Chabowski A., Coort S.L., Calles-Escandon J., Tandon N.N., Glatz J.F., Luiken J.J., Bonen A. FEBS Lett.579:2428-2432(2005) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION

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SKU	Supplier No.	Size	Your price	Quantity
BHE13810023	E12692r	96T	$796		Add to Cart

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