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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Tight junction protein ZO-1

SKU : BHE13811936

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E9600m
Alternative Names	Tight junction protein 1 ; Zona occludens protein 1 ; Zonula occludens protein 1 ; Zo1
Categories	Elisa
Function	The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells.
Specificity	Natural and recombinant Mouse Tight junction protein ZO-1
Subcellular Location	Cell membrane Peripheral membrane protein Cytoplasmic side Cell junction tight junction Cell junction gap junction Cytoplasm myofibril sarcomere I band Moves from the cytoplasm to the cell membrane concurrently with cell-cell contact. Detected at the leading edge of migrating and wounded cells.
Entryname	ZO1_MOUSE
Platform	PF00625
Protein Name	Tight junction protein ZO-1
Sequence	50: MSARAAAAKS ; TAMEETAIWE ; QHTVTLHRAP ; GFGFGIAISG ; GRDNPHFQSG ; 100: ETSIVISDVL ; KGGPAEGQLQ ; ENDRVAMVNG ; VSMDNVEHAF ; AVQQLRKSGK ; 150: NAKITIRRKK ; KVQIPVSHPD ; PEPVSDNEDD ; SYDEEVHDPR ; AGRGALANRR ; 200: SEKSWARDRS ; ASRERSLSPR ; SDRRSVASSQ ; PAKPTKVTLV ; KSRKNEEYGL ; 250: RLASHIFVKE ; ISQDSLAARD ; GNIQEGDVVL ; KINGTVTENM ; SLTDAKTLIE ; 300: RSKGKLKMVV ; QRDERATLLN ; VPDLSDSIHS ; ANASERDDIS ; EIQSLASDHS ; 350: GRSHDRPPRR ; SQSRSPDQRS ; EPSDHSTQSP ; QQPSNGSLRS ; REEERMSKPG ; 400: AISTPVKHVD ; DHPPKAVEEV ; TVEKNEKQTP ; TLPEPKPVYA ; QVGQPDVDLP ; 450: VSPSDGALPN ; SAHEDGILRP ; SMKLVKFRKG ; DSVGLRLAGG ; NDVGIFVAGV ; 500: LEDSPAAKEG ; LEEGDQILRV ; NNVDFTNIIR ; EEAVLFLLDL ; PKGEEVTILA ; 550: QKKKDVYRRI ; VESDVGDSFY ; IRTHFEYEKE ; SPYGLSFNKG ; EVFRVVDTLY ; 600: NGKLGSWLAI ; RIGKNHKEVE ; RGIIPNKNRA ; EQLASVQYTL ; PKTAGGDRAD ; 650: FWRFRGLRSS ; KRNLRKSRED ; LSAQPVQTKF ; PAYERVVLRE ; AGFLRPVTIF ; 700: GPIADVAREK ; LAREEPDIYQ ; IAKSEPRDAG ; TDHRSSGIIR ; LHTIKQIIDQ ; 750: DKHALLDVTP ; NAVDRLNYAQ ; WYPIVVFLNP ; DSKQGVKTMR ; MRLCPESRKS ; 800: ARKLYERSHK ; LRKNNHHLFT ; TTINLNSMND ; GWYGALKEAI ; QQQQNQLVWV ; 850: SEGKADGATS ; DDLDLHDDRL ; SYLSAPGSEY ; SMYSTDSRHT ; SDYEDTDTEG ; 900: GAYTDQELDE ; TLNDEVGTPP ; ESAITRSSEP ; VREDSSGMHH ; ENQTYPPYSP ; 950: QAQPQAIHRI ; DSPGLKPASQ ; QKAEASSPVP ; YLSPETTPAS ; SASAVNHNVS ; 1000: VTNVSLEEPA ; PAPPTSHASQ ; PGCLGAPSAE ; AAHVVLRGEG ; PPLPPHADPA ; 1050: KVYRKEPYSE ; EMMRQNHILK ; QPALGHPGQR ; PDKEPNLAYE ; PQLPYIEKQA ; 1100: SRDLEQPSYR ; YEVSSYTDQF ; SRNYDHRLRF ; EDRIPTYEDQ ; WSYYDDKQPY ; 1150: QPRPFENQHP ; RDLDSRQHPE ; EASERGYFQR ; FEEPAPLSYD ; SRTRYEQLPR ; 1200: TSTLRHEEQP ; APAYEVHNRY ; RPEAQPYSST ; GPKSSEPKQY ; FDQYPRSYEQ ; 1250: VPPPGFTSKT ; GHYEPLHGAA ; VVPPLIPSSQ ; QKPEVLPSAT ; KPQPPPPTLT ; 1300: EEEEDPAMKP ; QSVLTRVKMF ; ENKRSASLEN ; KKDVNDTASF ; KPPEVASKPP ; 1350: GASLAGPKPV ; PQSQFSEHDK ; TLYRLPEPQK ; PQVKPPEDIV ; RSNHYDPEED ; 1400: EEYYRKQLSY ; FDRRSFESKP ; SAHLPAGHHS ; EPAKPVHSQS ; QPNFSSYSSK ; 1450: GKPETDAVDR ; SFSEKRYDPA ; QATPPPPPLP ; SQYSQPAPPL ; SSSSLHIHSK ; 1500: GAQGEGNSVS ; LDFQNSYMSK ; PDPPPSQSKP ; ATFRPPTRED ; PPQTFYPQKS ; 1550: FPDKAPVNGA ; EQTQKTITPV ; YNRFTPKPYT ; SSARPFERKF ; ESPKFNHNLL ; 1600: PSETVHKPEL ; SSKTPTSPKT ; LMKAHSSTQP ; PEFDSGVETF ; SVHTDKPKYQ ; 1650: MNNISTMPKA ; VPVSPSAVEE ; DEDEDGHTVV ; ATARGIFNSN ; GGVLSSIETG ; 1700: VSIIIPQGAI ; PEGIEQEIYF ; KVCRDNSILP ; PLDKEKGETL ; LSPLVMCGPH ; 1745: GLKFLKPVEL ; RLPHCDPKTW ; QNKCLPGDPN ; YLVGANCVSV ; LIDHF
Sequence Length	1745
String	P39447
Sub Unit	Homodimer, and heterodimer with TJP2/ZO-2 and TJP3/ZO-3. Interacts with CGN/cingulin, CALM, CXADR, GJD3, HSPA4 and UBN1. Interacts (via ZU5 domain) with CDC42BPB. Interacts (via PDZ domain) with GJA1 (By similarity). Interacts with OCLN, claudins, GJA12 and KIRREL1. Interacts with BVES (via the C-terminus cytoplasmic tail). Interacts (via ZU5 domain) with GCOM1.

Uniprot	P39447
Gene Name	Tjp1
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:21872
Unigene	Mm.4342

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SKU	Supplier No.	Size	Your price	Quantity
BHE13811936	E9600m	96T	$776		Add to Cart

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