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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Non-receptor tyrosine-protein kinase TYK2

SKU : BHE13811506

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1595m
Categories	Elisa
Function	Involved in intracellular signal transduction by amplifying type I and type II IFN signaling. Phosphorylates the interferon-alpha/beta receptor alpha chain. Plays an essential role in promoting selective immune responses, including innate host defense mechanisms and specific antiviral activities.
Specificity	Natural and recombinant Mouse Non-receptor tyrosine-protein kinase TYK2
Detection Range	0.625-40ng/mL
Entryname	TYK2_MOUSE
Method Type	Sandwich
Platform	PF07714
Protein Name	Non-receptor tyrosine-protein kinase TYK2
Sensitivity	0.313ng/mL
Sequence	50: MPLCGRRAIL ; EDSKADGTEA ; QPLVPTGCLM ; VLLHWPGPEG ; GEPWVTFSQT ; 100: SLTAEEVCIH ; IAHKVGITPP ; CLNLFALYNA ; QAKVWLPPNH ; ILDTSQDMNL ; 150: YFRMRFYFRN ; WHGMNPQEPA ; VYRCGFPGAE ; TSSDRAEQGV ; QLLDSASFEY ; 200: LFEQGKHEFM ; NDVVSLRDLS ; SEEEIHHFKN ; ESLGMAFLHL ; CHLALSRGVP ; 250: LEEMAREISF ; KNCIPHSFRQ ; HIRQHNVLTR ; LRLHRVFRRF ; LRAFRPGHLS ; 300: QQVVMVKYLA ; TLERLAPRFG ; SERIPVCHLE ; VLAQPERDPC ; YIQNSGQTAG ; 350: DPGPELPSGP ; PTHEVLVTGT ; GGIQWHPLQT ; QESERGNSRG ; NPHGSRSGKK ; 400: PKAPKAGEHL ; TESPQEPPWT ; YFCDFQDISH ; VVLKERRVHI ; HLQDNKCLLL ; 450: CLCSQAEALS ; FVALVDGYFR ; LTADSSHYLC ; HEVAPPRLVT ; SIQNGIHGPL ; 500: MDPFVQAKLW ; PEDGLYLIQW ; STSHLHRLIL ; TVAHRNPAXS ; NGPRGLRLRK ; 550: FPITQQPGAF ; VLDGWGRSFA ; SLGDLRLALQ ; GCSLRAGDDC ; FPLHXCCLPR ; 600: PREISNLVIM ; RGSRAHTRPL ; NLSQLSFHRV ; HQDEITQLSH ; LGQGTRTNVY ; 650: EGLLRVGGPD ; EGKVDNGCPP ; EPGGTSGQQL ; RVVLKVLDPS ; HHDIALAFYE ; 700: XASLMSQVSH ; MHLAFLHGVC ; VRGSENIIVT ; EFVEHGPLDV ; WLRRQRGQVP ; 750: MTWKMVVAQQ ; LASALSYLED ; KNLVHGNVCG ; RNILLARLGL ; EEGTNPFIKL ; 800: SDPGVGQGAL ; SREERVERIP ; WTAPECLSGG ; TSSLGTATDM ; WGFGATLLEI ; 850: CFDGEAPLQG ; RGPSEKERFY ; TKKHQLPEPS ; CPELATLTRQ ; CLTYEPAQRP ; 900: SFRTILRDLT ; RLQPQNLVGT ; SAVNSDSPAS ; DPTVFHKRYL ; KKIRDLGEGH ; 950: FGKVSLYCYD ; PTNDGTGEMV ; AVKALKEGCG ; PQLRSGWQRE ; IEILRTLYHE ; 1000: HIVKYKGCCE ; DQGEKSVQLV ; MEYVPLGSLR ; DYLPRHCVGL ; AQLLLFAQQI ; 1050: CEGMAYLHAQ ; HYIHRDLAAR ; NVLLDNDRLV ; KIGDFGLAKA ; VPEGHEYYRV ; 1100: REDGDSPVFW ; YAPECLKECK ; FYYASDVWSF ; GVTLYELLTY ; CDSNQSPHTK ; 1150: FTELIGHTQG ; QMTVLRLTEL ; LERGERLPRP ; DRCPCEIYHL ; MKNCWETEAS ; 1180: FRPTFQNLVP ; ILQTAQEKYQ ; GQVPSVFSVC ;
Sequence Length	1180
String	Q9R117
Sub Unit	Interacts with JAKMIP1.

Uniprot	Q9R117
Gene Name	Tyk2
Immunogen Species	Mus musculus (Mouse)
Unigene	Mm.20249

Reference	1. "Partial impairment of cytokine responses in Tyk2-deficient mice." Karaghiosoff M., Neubauer H., Lassnig C., Kovarik P., Schindler H., Pircher H., McCoy B., Bogdan C., Decker T., Brem G., Pfeffer K., Mueller M. Immunity13:549-560(2000) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE strain: 129/Sv. tissue: Liver. 2. Lubec G., Sunyer B., Chen W.-Q. Submitted (2009-01) to the UniProtKB [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 732-737;IDENTIFICATION BY MASS SPECTROMETRY strain: OF1. tissue: Hippocampus. 3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 769-1180 4. "Quantitative time-resolved phosphoproteomic analysis of mast cell signaling." Cao L., Yu K., Banh C., Nguyen V., Ritz A., Raphael B.J., Kawakami Y., Kawakami T., Salomon A.R. J. Immunol.179:5864-5876(2007) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-600;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS] tissue: Mast cell. 5. "Enabling structure-based drug design of Tyk2 through co-crystallization with a stabilizing aminoindazole inhibitor." Argiriadi M.A., Goedken E.R., Banach D., Borhani D.W., Burchat A., Dixon R.W., Marcotte D., Overmeyer G., Pivorunas V., Sadhukhan R., Sousa S., Moore N.S., Tomlinson M., Voss J., Wang L., Wishart N., Woller K., Talanian R.V. BMC Struct. Biol.12:22-22(2012) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF 880-1170 IN COMPLEX WITH INHIBITOR

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SKU	Supplier No.	Size	Your price	Quantity
BHE13811506	E1595m	96T	$776		Add to Cart

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