ELISA Kit for Mouse Neuroendocrine protein 7B2

Mfr.No.

E9861m

Alternative Names

Secretogranin V ; Secretogranin-5 ; Secretory granule endocrine protein I ; Sgne-1 ; Sgne1

Categories

Elisa

Function

Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. Also required for cleavage of PCSK2 but does not appear to be involved in its folding. Plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro.

Specificity

Natural and recombinant Mouse Neuroendocrine protein 7B2

Subcellular Location

Secreted Neuroendocrine and endocrine secretory granules.

Detection Range

78-5000pg/mL

Entryname

7B2_MOUSE

Linearity

The linearity of the kit was assayed by testing samples spiked with appropriate concentration of ACE and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.

Sample	1：2	1:4	1:8	1:16
serum(n=5)	92-103%	93-104%	95-106%	92-107%
EDTA plasma(n=5)	89-97%	92-102%	91-98%	94-104%
heparin plasma(n=5)	91-103%	94-106%	101-108%	97-107%

Method Type

Sandwich

Platform

PF05281

Precision

Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

Intra-Assay CV: ≤ 4.7%

Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

Inter-Assay CV: ≤ 7.1%

Protein Name

Neuroendocrine protein 7B2

Recovery

Recovery was determined by spiking various levels of ACE into serum and plasma .

Sample Type	Average(%)	Recovery Range(%)
Serum	96	95-106
Plasma	97	94-103

Sensitivity

42pg/mL

Sequence

50:

MASRLVSAML ; SGLLFWLMFE ; WNPAFAYSPR ; TPDRVSETDI ; QRLLHGVMEQ ;

100:

LGIARPRVEY ; PAHQAMNLVG ; PQSIEGGAHE ; GLQHLGPFGN ; IPNIVAELTG ;

150:

DNIPKDFSED ; QGYPDPPNPC ; PLGKTADDGC ; LENAPDTAEF ; SREFQLDQHL ;

200:

FDPEHDYPGL ; GKWNKKLLYE ; KMKGGQRRKR ; RSVNPYLQGK ; RLDNVVAKKS ;

212:

VPHFSEEEKE ; AE

Sequence Length

212

String

P12961

Sub Unit

Interacts with PCSK2/PC2 early in the secretory pathway. Dissociation occurs at later stages.

Uniprot	P12961
Gene Name	Scg5
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:20394
Unigene	Mm.4836

Have you used this product?

Rate it now..!!

SKU	Supplier No.	Size	Your price	Quantity
BHE13800007	E9861m	96T	$776		Add to Cart

ELISA Kit for Mouse Neuroendocrine protein 7B2

Contact us to order

Tel

Email

Contact us to order

Tel

Email

Reviews of ELISA Kit for Mouse Neuroendocrine protein 7B2

Rate it now..!!