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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse NACHT, LRR and PYD domains-containing protein 3

SKU : BHE13808292

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E14531m
Alternative Names	Cold autoinflammatory syndrome 1 protein homolog ; Cryopyrin ; Mast cell maturation-associated-inducible protein 1 ; PYRIN-containing APAF1-like protein 1 ; Cias1 ; Mmig1 ; Nalp3 ; Pypaf1
Categories	Elisa
Function	May function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65. Also inhibits transcriptional activity of RELA (By similarity). Activates caspase-1 as part of the NALP3 inflammasome complex in response to a number of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18.
Specificity	Natural and recombinant Mouse NACHT, LRR and PYD domains-containing protein 3
Subcellular Location	Cytoplasm
Detection Range	0.156-10ng/mL
Entryname	NALP3_MOUSE
Method Type	Sandwich
Platform	PF02758
Protein Name	NACHT, LRR and PYD domains-containing protein 3
Sensitivity	0.058ng/mL
Sequence	50: MTSVRCKLAQ ; YLEDLEDVDL ; KKFKMHLEDY ; PPEKGCIPVP ; RGQMEKADHL ; 100: DLATLMIDFN ; GEEKAWAMAV ; WIFAAINRRD ; LWEKAKKDQP ; EWNDTCTSHS ; 150: SMVCQEDSLE ; EEWMGLLGYL ; SRISICKKKK ; DYCKMYRRHV ; RSRFYSIKDR ; 200: NARLGESVDL ; NSRYTQLQLV ; KEHPSKQERE ; HELLTIGRTK ; MRDSPMSSLK ; 250: LELLFEPEDG ; HSEPVHTVVF ; QGAAGIGKTI ; LARKIMLDWA ; LGKLFKDKFD ; 300: YLFFIHCREV ; SLRTPRSLAD ; LIVSCWPDPN ; PPVCKILRKP ; SRILFLMDGF ; 350: DELQGAFDEH ; IGEVCTDWQK ; AVRGDILLSS ; LIRKKLLPKA ; SLLITTRPVA ; 400: LEKLQHLLDH ; PRHVEILGFS ; EAKRKEYFFK ; YFSNELQARE ; AFRLIQENEV ; 450: LFTMCFIPLV ; CWIVCTGLKQ ; QMETGKSLAQ ; TSKTTTAVYV ; FFLSSLLQSR ; 500: GGIEEHLFSD ; YLQGLCSLAA ; DGIWNQKILF ; EECDLRKHGL ; QKTDVSAFLR ; 550: MNVFQKEVDC ; ERFYSFSHMT ; FQEFFAAMYY ; LLEEEAEGET ; VRKGPGGCSD ; 600: LLNRDVKVLL ; ENYGKFEKGY ; LIFVVRFLFG ; LVNQERTSYL ; EKKLSCKISQ ; 650: QVRLELLKWI ; EVKAKAKKLQ ; WQPSQLELFY ; CLYEMQEEDF ; VQSAMDHFPK ; 700: IEINLSTRMD ; HVVSSFCIKN ; CHRVKTLSLG ; FFHNSPKEEE ; EERRGGRPLD ; 750: QVQCVFPDTH ; VACSSRLVNC ; CLTSSFCRGL ; FSSLSTNRSL ; TELDLSDNTL ; 800: GDPGMRVLCE ; ALQHPGCNIQ ; RLWLGRCGLS ; HQCCFDISSV ; LSSSQKLVEL ; 850: DLSDNALGDF ; GIRLLCVGLK ; HLLCNLQKLW ; LVSCCLTSAC ; CQDLALVLSS ; 900: NHSLTRLYIG ; ENALGDSGVQ ; VLCEKMKDPQ ; CNLQKLGLVN ; SGLTSICCSA ; 950: LTSVLKTNQN ; FTHLYLRSNA ; LGDTGLRLLC ; EGLLHPDCKL ; QMLELDNCSL ; 1000: TSHSCWNLST ; ILTHNHSLRK ; LNLGNNDLGD ; LCVVTLCEVL ; KQQGCLLQSL ; 1033: QLGEMYLNRE ; TKRALEALQE ; EKPELTIVFE ; ISW
Sequence Length	1033
String	Q8R4B8
Sub Unit	Interacts with PYCARD/ASC. Part of the NALP3 inflammasome complex which is involved in activation of caspase-1 and caspase-5, leading to processing of IL1B and IL18.

Uniprot	Q8R4B8
Gene Name	Nlrp3
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:216799
Unigene	Mm.54174

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SKU	Supplier No.	Size	Your price	Quantity
BHE13808292	E14531m	96T	$776		Add to Cart

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