Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules.
Specificity
Natural and recombinant Mouse Monocyte differentiation antigen CD14
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF 20-329;DISULFIDE BONDS;GLYCOSYLATION AT ASN-147; ASN-180 AND ASN-276;DOMAINS LEUCINE-RICH REPEATS
Reviews of ELISA Kit for Mouse Monocyte differentiation antigen CD14