ELISA Kit for Mouse Interleukin-6 receptor subunit alpha

Mfr.No.	E1815m
Alternative Names	IL-6R 1 ; CD126 ; Il6r
Categories	Elisa
Function	Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis.
Specificity	Natural and recombinant Mouse Interleukin-6 receptor subunit alpha
Subcellular Location	Membrane Single-pass type I membrane protein
Detection Range	78-5000pg/mL
Entryname	IL6RA_MOUSE
Method Type	Sandwich
Platform	PF00047
Protein Name	Interleukin-6 receptor subunit alpha
Sensitivity	40.5pg/mL
Sequence	50: MLTVGCTLLV ; ALLAAPAVAL ; VLGSCRALEV ; ANGTVTSLPG ; ATVTLICPGK ; 100: EAAGNVTIHW ; VYSGSQNREW ; TTTGNTLVLR ; DVQLSDTGDY ; LCSLNDHLVG ; 150: TVPLLVDVPP ; EEPKLSCFRK ; NPLVNAICEW ; RPSSTPSPTT ; KAVLFAKKIN ; 200: TTNGKSDFQV ; PCQYSQQLKS ; FSCQVEILEG ; DKVYHIVSLC ; VANSVGSKSS ; 250: HNEAFHSLKM ; VQPDPPANLV ; VSAIPGRPRW ; LKVSWQHPET ; WDPSYYLLQF ; 300: QLRYRPVWSK ; EFTVLLLPVA ; QYQCVIHDAL ; RGVKHVVQVR ; GKEELDLGQW ; 350: SEWSPEVTGT ; PWIAEPRTTP ; AGILWNPTQV ; SVEDSANHED ; QYESSTEATS ; 400: VLAPVQESSS ; MSLPTFLVAG ; GSLAFGLLLC ; VFIILRLKQK ; WKSEAEKESK ; 450: TTSPPPPPYS ; LGPLKPTFLL ; VPLLTPHSSG ; SDNTVNHSCL ; GVRDAQSPYD ; 460: NSNRDYLFPR ;
Sequence Length	460
String	P22272
Sub Unit	Hexamer of two molecules each of IL6, IL6R and IL6ST.

Reference	1. "Functional murine interleukin 6 receptor with the intracisternal A particle gene product at its cytoplasmic domain. Its possible role in plasmacytomagenesis." Sugita T., Totsuka T., Saito M., Yamasaki K., Taga T., Hirano T., Kishimoto T. J. Exp. Med.171:2001-2009(1990) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: BALB/c. tissue: Spleen. 2. Fiorillo M.T., Ciliberto G., Dente L. Submitted (1990-07) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: C3H. tissue: Liver.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13805579	E1815m	96T	$776		Add to Cart