ELISA Kit for Mouse Corticosteroid 11-beta-dehydrogenase isozyme 2

Mfr.No.	E11618m
Alternative Names	11-beta-hydroxysteroid dehydrogenase type 2 ; 11-DH2 ; NAD-dependent 11-beta-hydroxysteroid dehydrogenase ; Hsd11k
Categories	Elisa
Function	Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.
Specificity	Natural and recombinant Mouse Corticosteroid 11-beta-dehydrogenase isozyme 2
Subcellular Location	Microsome Endoplasmic reticulum
Entryname	DHI2_MOUSE
Platform	PF00106
Protein Name	Corticosteroid 11-beta-dehydrogenase isozyme 2
Sequence	50: MERWPWPSGG ; AWLLVAARAL ; LQLLRSDLRL ; GRPLLAALAL ; LAALDWLCQR ; 100: LLPPPAALVV ; LAGAGWIALS ; RLARPPRLPV ; ATRAVLITGC ; DTGFGKETAK ; 150: KLDAMGFTVL ; ATVLDLNSPG ; ALELRDLCSP ; RLKLLQMDLT ; KAEDISRVLE ; 200: ITKAHTASTG ; LWGLVNNAGL ; NIVVADVELS ; PVATFRKCME ; VNFFGALELT ; 250: KGLLPLLRHS ; RGRIVTVGSP ; AGDMPYPCLA ; AYGTSKAAIA ; LLMDTFGCEL ; 300: LPWGIKVSII ; KPGCFKTDAV ; TNVNLWEKRK ; QLLLANIPRE ; LLQAYGEDYI ; 350: EHVHGQFLNS ; LRMALPDLSP ; VVDAIIDALL ; AAQPRSRYYP ; GRGLGLMYFI ; 386: HHYLPEGLRR ; CFLQNFFINH ; LLPRALRPGQ ; HGPAPA
Sequence Length	386
String	P51661
Sub Unit	Interacts with ligand-free cytoplasmic NR3C2.

Reference	1. "Cloning of the mouse 11 beta-hydroxysteroid dehydrogenase type 2 gene: tissue specific expression and localization in distal convoluted tubules and collecting ducts of the kidney." Cole T.J. Endocrinology136:4693-4696(1995) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] strain: 129/Sv. 2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] tissue: Kidney.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13803655	E11618m	96T	$776		Add to Cart