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Home / Assay Kits / ELISA Kits

ELISA Kit for Mouse Antigen peptide transporter 2

SKU : BHE13810973

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E10018m
Alternative Names	ATP-binding cassette sub-family B member 3 ; Histocompatibility antigen modifier 2 ; Abcb3 ; Ham-2 ; Ham2
Categories	Elisa
Function	Involved in the transport of antigens from the cytoplasm to the endoplasmic reticulum for association with MHC class I molecules. Also acts as a molecular scaffold for the final stage of MHC class I folding, namely the binding of peptide. Nascent MHC class I molecules associate with TAP via tapasin.
Specificity	Natural and recombinant Mouse Antigen peptide transporter 2
Subcellular Location	Endoplasmic reticulum membrane Multi-pass membrane protein The transmembrane segments seem to form a pore in the membrane.
Detection Range	0.312-20ng/mL
Entryname	TAP2_MOUSE
Method Type	Sandwich
Platform	PF00664
Protein Name	Antigen peptide transporter 2
Sensitivity	0.194ng/mL
Sequence	50: MALSYLRPWV ; SLLLADMALL ; GLLQGSLGNL ; LPQGLPGLWI ; EGTLRLGVLW ; 100: GLLKVGELLG ; LVGTLLPLLC ; LATPLFFSLR ; ALVGGTASTS ; VVRVASASWG ; 150: WLLAGYGAVA ; LSWAVWAVLS ; PAGVQEKEPG ; QENRTLMKRL ; LKLSRPDLPF ; 200: LIAAFFFLVV ; AVWGETLIPR ; YSGRVIDILG ; GDFDPDAFAS ; AIFFMCLFSV ; 250: GSSFSAGCRG ; GSFLFTMSRI ; NLRIREQLFS ; SLLRQDLGFF ; QETKTGELNS ; 300: RLSSDTSLMS ; RWLPFNANIL ; LRSLVKVVGL ; YFFMLQVSPR ; LTFLSLLDLP ; 350: LTIAAEKVYN ; PRHQAVLKEI ; QDAVAKAGQV ; VREAVGGLQT ; VRSFGAEEQE ; 400: VSHYKEALER ; CRQLWWRRDL ; EKDVYLVIRR ; VMALGMQVLI ; LNCGVQQILA ; 450: GEVTRGGLLS ; FLLYQEEVGQ ; YVRNLVYMYG ; DMLSNVGAAE ; KVFSYLDRKP ; 500: NLPQPGILAP ; PWLEGRVEFQ ; DVSFSYPRRP ; EKPVLQGLTF ; TLHPGTVTAL ; 550: VGPNGSGKST ; VAALLQNLYQ ; PTGGQLLLDG ; EPLTEYDHHY ; LHRQVVLVGQ ; 600: EPVLFSGSVK ; DNIAYGLRDC ; EDAQVMAAAQ ; AACADDFIGE ; MTNGINTEIG ; 650: EKGGQLAVGQ ; KQRLAIARAL ; VRNPRVLILD ; EATSALDAQC ; EQALQNWRSQ ; 700: GDRTMLVIAH ; RLHTVQNADQ ; VLVLKQGRLV ; EHDQLRDGQD ; VYAHLVQQRL ; 702: EA
Sequence Length	702
String	P36371
Sub Unit	Heterodimer of TAP1 and TAP2.

Uniprot	P36371
Gene Name	Tap2
Immunogen Species	Mus musculus (Mouse)
Kegg	mmu:21355
Unigene	Mm.14814

Reference	1. "Major histocompatibility complex (MHC)-encoded HAM2 is necessary for antigenic peptide loading onto class I MHC molecules." Yang Y., Frueh K., Chambers J., Waters J.B., Wu L., Spies T., Peterson P.A. J. Biol. Chem.267:11669-11672(1992) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]

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SKU	Supplier No.	Size	Your price	Quantity
BHE13810973	E10018m	96T	$776		Add to Cart

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