ELISA Kit for Human Tumor necrosis factor ligand superfamily member 9

Mfr.No.	E10632h
Alternative Names	4-1BB ligand ; 4-1BBL
Categories	Elisa
Function	Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages.
Specificity	Natural and recombinant Human Tumor necrosis factor ligand superfamily member 9
Subcellular Location	Membrane Single-pass type II membrane protein
Entryname	TNFL9_HUMAN
Platform	PF00229
Protein Name	Tumor necrosis factor ligand superfamily member 9
Sequence	50: MEYASDASLD ; PEAPWPPAPR ; ARACRVLPWA ; LVAGLLLLLL ; LAAACAVFLA ; 100: CPWAVSGARA ; SPGSAASPRL ; REGPELSPDD ; PAGLLDLRQG ; MFAQLVAQNV ; 150: LLIDGPLSWY ; SDPGLAGVSL ; TGGLSYKEDT ; KELVVAKAGV ; YYVFFQLELR ; 200: RVVAGEGSGS ; VSLALHLQPL ; RSAAGAAALA ; LTVDLPPASS ; EARNSAFGFQ ; 250: GRLLHLSAGQ ; RLGVHLHTEA ; RARHAWQLTQ ; GATVLGLFRV ; TPEIPAGLPS ; 254: PRSE
Sequence Length	254
String	P41273
Sub Unit	Homotrimer.

Reference	1. "Molecular and biological characterization of human 4-1BB and its ligand." Alderson M.R., Smith C.A., Tough T.W., Davis-Smith T., Armitage R.J., Falk B., Roux E., Baker E., Sutherland G.R., Din W.S., Goodwin R.G. Eur. J. Immunol.24:2219-2227(1994) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] 2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] tissue: Lung. 3. "The structure of the trimer of human 4-1BB ligand is unique among members of the tumor necrosis factor superfamily." Won E.Y., Cha K., Byun J.S., Kim D.U., Shin S., Ahn B., Kim Y.H., Rice A.J., Walz T., Kwon B.S., Cho H.S. J. Biol. Chem.285:9202-9210(2010) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) OF 80-246;FUNCTION;SUBUNIT

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SKU	Supplier No.	Size	Your price	Quantity
BHE13811554	E10632h	96T	$736		Add to Cart