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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Transferrin receptor protein 1

SKU : BHE13810195

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0809h
Alternative Names	T9 ; p90 ; CD71
Categories	Elisa
Function	Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.
Specificity	Natural and recombinant Human Transferrin receptor protein 1
Subcellular Location	Transferrin receptor protein 1, serum form Secreted
Detection Range	3.12-200ng/mL
Entryname	TFR1_HUMAN
Method Type	Sandwich
Platform	PF02225
Protein Name	Transferrin receptor protein 1
Sensitivity	1ng/mL
Sequence	50: MMDQARSAFS ; NLFGGEPLSY ; TRFSLARQVD ; GDNSHVEMKL ; AVDEEENADN ; 100: NTKANVTKPK ; RCSGSICYGT ; IAVIVFFLIG ; FMIGYLGYCK ; GVEPKTECER ; 150: LAGTESPVRE ; EPGEDFPAAR ; RLYWDDLKRK ; LSEKLDSTDF ; TGTIKLLNEN ; 200: SYVPREAGSQ ; KDENLALYVE ; NQFREFKLSK ; VWRDQHFVKI ; QVKDSAQNSV ; 250: IIVDKNGRLV ; YLVENPGGYV ; AYSKAATVTG ; KLVHANFGTK ; KDFEDLYTPV ; 300: NGSIVIVRAG ; KITFAEKVAN ; AESLNAIGVL ; IYMDQTKFPI ; VNAELSFFGH ; 350: AHLGTGDPYT ; PGFPSFNHTQ ; FPPSRSSGLP ; NIPVQTISRA ; AAEKLFGNME ; 400: GDCPSDWKTD ; STCRMVTSES ; KNVKLTVSNV ; LKEIKILNIF ; GVIKGFVEPD ; 450: HYVVVGAQRD ; AWGPGAAKSG ; VGTALLLKLA ; QMFSDMVLKD ; GFQPSRSIIF ; 500: ASWSAGDFGS ; VGATEWLEGY ; LSSLHLKAFT ; YINLDKAVLG ; TSNFKVSASP ; 550: LLYTLIEKTM ; QNVKHPVTGQ ; FLYQDSNWAS ; KVEKLTLDNA ; AFPFLAYSGI ; 600: PAVSFCFCED ; TDYPYLGTTM ; DTYKELIERI ; PELNKVARAA ; AEVAGQFVIK ; 650: LTHDVELNLD ; YERYNSQLLS ; FVRDLNQYRA ; DIKEMGLSLQ ; WLYSARGDFF ; 700: RATSRLTTDF ; GNAEKTDRFV ; MKKLNDRVMR ; VEYHFLSPYV ; SPKESPFRHV ; 750: FWGSGSHTLP ; ALLENLKLRK ; QNNGAFNETL ; FRNQLALATW ; TIQGAANALS ; 760: GDVWDIDNEF ;
Sequence Length	760
String	P02786
Sub Unit	Homodimer; disulfide-linked. Binds one transferrin or HFE molecule per subunit. Binds the HLA class II histocompatibility antigen, DR1. Interacts with SH3BP3. Interacts with Machupo arenavirus GPC.

Uniprot	P02786
Gene Name	TFRC
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:7037
Unigene	Hs.529618

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SKU	Supplier No.	Size	Your price	Quantity
BHE13810195	E0809h	96T	$536		Add to Cart

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