Calcyclin ; Growth factor-inducible protein 2A9 ; MLN 4 ; Prolactin receptor-associated protein ; PRA ; S100 calcium-binding protein A6 ; CACY
Categories
Elisa
Function
May function as calcium sensor and contribute to cellular calcium signaling (Potential). May function by interacting with other proteins and indirectly play a role in the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative.
Specificity
Natural and recombinant Human Protein S100-A6
Subcellular Location
Nucleus envelope Cytoplasm Cell membrane Peripheral membrane protein Cytoplasmic side
Homodimer; head to tail assembly of 2 subunits. Interacts with CACYBP (By similarity). Interacts with ANXA2 and ANXA11 (via N-terminus). Interacts with SUGT1. Interacts with TP53; has higher affinity for TP53 that is phosphorylated on its N-terminal domain, and lower affinity for TP53 that is phosphorylated on its C-terminal domain. Interacts with tropomyosin. Interacts with FKBP4.