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ELISA Kit for Human Pro-interleukin-16

SKU : BHE13805648

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0062h
Categories	Elisa
Function	Isoform 3 is involved in cell cycle progression in T-cells. Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene. May act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells.
Specificity	Natural and recombinant Human Pro-interleukin-16
Subcellular Location	Isoform 3 Cytoplasm Nucleus
Detection Range	15.6-1000pg/mL
Entryname	IL16_HUMAN
Method Type	Sandwich
Platform	PF00595
Protein Name	Pro-interleukin-16
Sensitivity	10pg/mL
Sequence	50: MESHSRAGKS ; RKSAKFRSIS ; RSLMLCNAKT ; SDDGSSPDEK ; YPDPFEISLA ; 100: QGKEGIFHSS ; VQLADTSEAG ; PSSVPDLALA ; SEAAQLQAAG ; NDRGKTCRRI ; 150: FFMKESSTAS ; SREKPGKLEA ; QSSNFLFPKA ; CHQRARSNST ; SVNPYCTREI ; 200: DFPMTKKSAA ; PTDRQPYSLC ; SNRKSLSQQL ; DCPAGKAAGT ; SRPTRSLSTA ; 250: QLVQPSGGLQ ; ASVISNIVLM ; KGQAKGLGFS ; IVGGKDSIYG ; PIGIYVKTIF ; 300: AGGAAAADGR ; LQEGDEILEL ; NGESMAGLTH ; QDALQKFKQA ; KKGLLTLTVR ; 350: TRLTAPPSLC ; SHLSPPLCRS ; LSSSTCITKD ; SSSFALESPS ; APISTAKPNY ; 400: RIMVEVSLQK ; EAGVGLGIGL ; CSVPYFQCIS ; GIFVHTLSPG ; SVAHLDGRLR ; 450: CGDEIVEISD ; SPVHCLTLNE ; VYTILSHCDP ; GPVPIIVSRH ; PDPQVSEQQL ; 500: KEAVAQAVEN ; TKFGKERHQW ; SLEGVKRLES ; SWHGRPTLEK ; EREKNSAPPH ; 550: RRAQKVMIRS ; SSDSSYMSGS ; PGGSPGSGSA ; EKPSSDVDIS ; THSPSLPLAR ; 600: EPVVLSIASS ; RLPQESPPLP ; ESRDSHPPLR ; LKKSFEILVR ; KPMSSKPKPP ; 650: PRKYFKSDSD ; PQKSLEEREN ; SSCSSGHTPP ; TCGQEARELL ; PLLLPQEDTA ; 700: GRSPSASAGC ; PGPGIGPQTK ; SSTEGEPGWR ; RASPVTQTSP ; IKHPLLKRQA ; 750: RMDYSFDTTA ; EDPWVRISDC ; IKNLFSPIMS ; ENHGHMPLQP ; NASLNEEEGT ; 800: QGHPDGTPPK ; LDTANGTPKV ; YKSADSSTVK ; KGPPVAPKPA ; WFRQSLKGLR ; 850: NRASDPRGLP ; DPALSTQPAP ; ASREHLGSHI ; RASSSSSSIR ; QRISSFETFG ; 900: SSQLPDKGAQ ; RLSLQPSSGE ; AAKPLGKHEE ; GRFSGLLGRG ; AAPTLVPQQP ; 950: EQVLSSGSPA ; ASEARDPGVS ; ESPPPGRQPN ; QKTLPPGPDP ; LLRLLSTQAE ; 1000: ESQGPVLKMP ; SQRARSFPLT ; RSQSCETKLL ; DEKTSKLYSI ; SSQVSSAVMK ; 1050: SLLCLPSSIS ; CAQTPCIPKE ; GASPTSSSNE ; DSAANGSAET ; SALDTGFSLN ; 1100: LSELREYTEG ; LTEAKEDDDG ; DHSSLQSGQS ; VISLLSSEEL ; KKLIEEVKVL ; 1150: DEATLKQLDG ; IHVTILHKEE ; GAGLGFSLAG ; GADLENKVIT ; VHRVFPNGLA ; 1200: SQEGTIQKGN ; EVLSINGKSL ; KGTTHHDALA ; ILRQAREPRQ ; AVIVTRKLTP ; 1250: EAMPDLNSST ; DSAASASAAS ; DVSVESTAEA ; TVCTVTLEKM ; SAGLGFSLEG ; 1300: GKGSLHGDKP ; LTINRIFKGA ; ASEQSETVQP ; GDEILQLGGT ; AMQGLTRFEA ; 1332: WNIIKALPDG ; PVTIVIRRKS ; LQSKETTAAG ; DS
Sequence Length	1332
String	Q14005
Sub Unit	Homotetramer (Probable). According to PubMed:9699630, the formation of a homotetrameric protein complex is not required for the chemo-attractant function. Isoform 3 interacts (via PDZ 3 domain) with PPP1R12A, PPP1R12B and PPP1R12C. Isoform 1 interacts with PPP1R12B. Isoform 3 interacts with GRIN2A. Isoform 3 interacts with GABPB1. Isoform 3 interacts (via PDZ 3 domain) with HDAC3. Isoform 1 interacts with GRIN2D, KCNJ10, KCNJ15 and CACNA1C (By similarity). Isoform 3 interacts with HTLV-1 tax.

Uniprot	Q14005
Gene Name	IL16
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:3603
Unigene	Hs.459095

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SKU	Supplier No.	Size	Your price	Quantity
BHE13805648	E0062h	96T	$536		Add to Cart

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