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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Neuronal calcium sensor 1

SKU : BHE13808196

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E13770h
Alternative Names	Frequenin homolog ; Frequenin-like protein ; Frequenin-like ubiquitous protein ; FLUP ; FREQ
Categories	Elisa
Function	Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Directly regulates GRK1 (RHOK), but not GRK2 to GRK5. Can substitute for calmodulin (By similarity). Stimulates PI4KB kinase activity (By similarity). Involved in long-term synaptic plasticity through its interaction with PICK1 (By similarity). May also play a role in neuron differentiation through inhibition of the activity of N-type voltage-gated calcium channel.
Specificity	Natural and recombinant Human Neuronal calcium sensor 1
Subcellular Location	Golgi apparatus Golgi stack membrane Peripheral membrane protein Cell junction synapse postsynaptic cell membrane postsynaptic density Cytoplasm perinuclear region Cell membrane Peripheral membrane protein Associated with Golgi stacks. Post-synaptic densities of dendrites, and in the pre-synaptic nerve terminal at neuromuscular junctions.
Detection Range	0.312-20ng/mL
Entryname	NCS1_HUMAN
Method Type	Sandwich
Platform	PF00036
Protein Name	Neuronal calcium sensor 1
Sensitivity	0.164ng/mL
Sequence	50: MGKSNSKLKP ; EVVEELTRKT ; YFTEKEVQQW ; YKGFIKDCPS ; GQLDAAGFQK ; 100: IYKQFFPFGD ; PTKFATFVFN ; VFDENKDGRI ; EFSEFIQALS ; VTSRGTLDEK ; 150: LRWAFKLYDL ; DNDGYITRNE ; MLDIVDAIYQ ; MVGNTVELPE ; EENTPEKRVD ; 190: RIFAMMDKNA ; DGKLTLQEFQ ; EGSKADPSIV ; QALSLYDGLV ;
Sequence Length	190
String	P62166
Sub Unit	Interacts with KCND2. Interacts in a calcium-independent manner with PI4KB. This binding competes with CALN2/CABP7 binding to PI4KB (By similarity). Interacts with ARF1, ARF3, ARF5 and ARF6. Interacts in a calcium-dependent manner with PICK1 (via AH domain) (By similarity). Interacts with IL1RAPL1.

Uniprot	P62166
Gene Name	NCS1
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:23413
Unigene	Hs.642946

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SKU	Supplier No.	Size	Your price	Quantity
BHE13808196	E13770h	96T	$736		Add to Cart

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