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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Glutamate receptor 1

SKU : BHE13804952

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E11293h
Alternative Names	AMPA-selective glutamate receptor 1 ; GluR-A ; GluR-K1 ; Glutamate receptor ionotropic ; AMPA 1 ; GluA1 ; GLUH1 ; GLUR1
Categories	Elisa
Function	Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
Specificity	Natural and recombinant Human Glutamate receptor 1
Subcellular Location	Cell membrane Multi-pass membrane protein Endoplasmic reticulum membrane Multi-pass membrane protein Cell junction synapse postsynaptic cell membrane Multi-pass membrane protein Cell junction synapse postsynaptic cell membrane postsynaptic density Cell projection dendrite Cell projection dendritic spine Interaction with CACNG2, CNIH2 and CNIH3 promotes cell surface expression.
Detection Range	0.156-10ng/mL
Entryname	GRIA1_HUMAN
Method Type	Sandwich
Platform	PF01094
Protein Name	Glutamate receptor 1
Sensitivity	0.061ng/mL
Sequence	50: MQHIFAFFCT ; GFLGAVVGAN ; FPNNIQIGGL ; FPNQQSQEHA ; AFRFALSQLT ; 100: EPPKLLPQID ; IVNISDSFEM ; TYRFCSQFSK ; GVYAIFGFYE ; RRTVNMLTSF ; 150: CGALHVCFIT ; PSFPVDTSNQ ; FVLQLRPELQ ; DALISIIDHY ; KWQKFVYIYD ; 200: ADRGLSVLQK ; VLDTAAEKNW ; QVTAVNILTT ; TEEGYRMLFQ ; DLEKKKERLV ; 250: VVDCESERLN ; AILGQIIKLE ; KNGIGYHYIL ; ANLGFMDIDL ; NKFKESGANV ; 300: TGFQLVNYTD ; TIPAKIMQQW ; KNSDARDHTR ; VDWKRPKYTS ; ALTYDGVKVM ; 350: AEAFQSLRRQ ; RIDISRRGNA ; GDCLANPAVP ; WGQGIDIQRA ; LQQVRFEGLT ; 400: GNVQFNEKGR ; RTNYTLHVIE ; MKHDGIRKIG ; YWNEDDKFVP ; AATDAQAGGD ; 450: NSSVQNRTYI ; VTTILEDPYV ; MLKKNANQFE ; GNDRYEGYCV ; ELAAEIAKHV ; 500: GYSYRLEIVS ; DGKYGARDPD ; TKAWNGMVGE ; LVYGRADVAV ; APLTITLVRE ; 550: EVIDFSKPFM ; SLGISIMIKK ; PQKSKPGVFS ; FLDPLAYEIW ; MCIVFAYIGV ; 600: SVVLFLVSRF ; SPYEWHSEEF ; EEGRDQTTSD ; QSNEFGIFNS ; LWFSLGAFMQ ; 650: QGCDISPRSL ; SGRIVGGVWW ; FFTLIIISSY ; TANLAAFLTV ; ERMVSPIESA ; 700: EDLAKQTEIA ; YGTLEAGSTK ; EFFRRSKIAV ; FEKMWTYMKS ; AEPSVFVRTT ; 750: EEGMIRVRKS ; KGKYAYLLES ; TMNEYIEQRK ; PCDTMKVGGN ; LDSKGYGIAT ; 800: PKGSALRNPV ; NLAVLKLNEQ ; GLLDKLKNKW ; WYDKGECGSG ; GGDSKDKTSA ; 850: LSLSNVAGVF ; YILIGGLGLA ; MLVALIEFCY ; KSRSESKRMK ; GFCLIPQQSI ; 900: NEAIRTSTLP ; RNSGAGASSG ; GSGENGRVVS ; HDFPKSMQSI ; PCMSHSSGMP ; 906: LGATGL
Sequence Length	906
String	P42261
Sub Unit	Homotetramer or heterotetramer of pore-forming glutamate receptor subunits. Tetramers may be formed by the dimerization of dimers. Interacts with DLG1 via its C-terminus. Interacts with SYNDIG1 and GRIA2 (By similarity). Interacts with LRFN1 (By similarity). Interacts with HIP1 and RASGRF2 (By similarity). Found in a complex with GRIA2, GRIA3, GRIA4, CNIH2, CNIH3, CACNG2, CACNG3, CACNG4, CACNG5, CACNG7 and CACNG8 (By similarity). Interacts with CACNG5 (By similarity). Interacts with CNIH2 and CACNG2.

Uniprot	P42261
Gene Name	GRIA1
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:2890
Unigene	Hs.519693

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SKU	Supplier No.	Size	Your price	Quantity
BHE13804952	E11293h	96T	$736		Add to Cart

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