17 kDa heparin-binding growth factor-binding protein ; 17 kDa HBGF-binding protein ; FGFBP ; HBP17
Categories
Elisa
Function
Acts as a carrier protein that release fibroblast-binding factors (FGFs) from the extracellular matrix (EM) storage and thus enhance the mitogenic activity of FGFs. Enhances FGF2 signaling during tissue repair, angiogenesis and in tumor growth.
Specificity
Natural and recombinant Human Fibroblast growth factor-binding protein 1
Subcellular Location
Secreted extracellular space Cell membrane Peripheral membrane protein Extracellular and plasma membrane-associated. Colocalizes with HSPG2 in the pericellular environment of squamous cell carcinomas.