Acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator. Able to regulate vascular remodeling and angiogenesis. Its similarity with UPP synthase proteins suggests that it may act as a scaffold for the binding of isoprenyl lipids and/or prenylated proteins.
Specificity
Natural and recombinant Human Dehydrodolichyl diphosphate synthase complex subunit NUS1
Subcellular Location
Membrane Single-pass type I membrane protein Colocalizes with Nogo-B during VEGF and wound healing angiogenesis.