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Home / Assay Kits / ELISA Kits

ELISA Kit for Human C4b-binding protein alpha chain

SKU : BHE13801746

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0761h
Alternative Names	Proline-rich protein ; PRP ; C4BP
Categories	Elisa
Function	Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. Alpha chain binds C4b. It interacts also with anticoagulant protein S and with serum amyloid P component.
Specificity	Natural and recombinant Human C4b-binding protein alpha chain
Subcellular Location	Secreted
Detection Range	1.56-100ng/mL
Entryname	C4BPA_HUMAN
Method Type	Sandwich
Platform	PF00084
Protein Name	C4b-binding protein alpha chain
Sensitivity	0.56ng/mL
Sequence	50: MHPPKTPSGA ; LHRKRKMAAW ; PFSRLWKVSD ; PILFQMTLIA ; ALLPAVLGNC ; 100: GPPPTLSFAA ; PMDITLTETR ; FKTGTTLKYT ; CLPGYVRSHS ; TQTLTCNSDG ; 150: EWVYNTFCIY ; KRCRHPGELR ; NGQVEIKTDL ; SFGSQIEFSC ; SEGFFLIGST ; 200: TSRCEVQDRG ; VGWSHPLPQC ; EIVKCKPPPD ; IRNGRHSGEE ; NFYAYGFSVT ; 250: YSCDPRFSLL ; GHASISCTVE ; NETIGVWRPS ; PPTCEKITCR ; KPDVSHGEMV ; 300: SGFGPIYNYK ; DTIVFKCQKG ; FVLRGSSVIH ; CDADSKWNPS ; PPACEPNSCI ; 350: NLPDIPHASW ; ETYPRPTKED ; VYVVGTVLRY ; RCHPGYKPTT ; DEPTTVICQK ; 400: NLRWTPYQGC ; EALCCPEPKL ; NNGEITQHRK ; SRPANHCVYF ; YGDEISFSCH ; 450: ETSRFSAICQ ; GDGTWSPRTP ; SCGDICNFPP ; KIAHGHYKQS ; SSYSFFKEEI ; 500: IYECDKGYIL ; VGQAKLSCSY ; SHWSAPAPQC ; KALCRKPELV ; NGRLSVDKDQ ; 550: YVEPENVTIQ ; CDSGYGVVGP ; QSITCSGNRT ; WYPEVPKCEW ; ETPEGCEQVL ; 597: TGKRLMQCLP ; NPEDVKMALE ; VYKLSLEIEQ ; LELQRDSARQ ; STLDKEL
Sequence Length	597
String	P04003
Sub Unit	Disulfide-linked complex of alpha and beta chains of 3 possible sorts: a 570 kDa complex of 7 alpha chains and 1 beta chain, a 530 kDa homoheptamer of alpha chains or a 500 kDa complex of 6 alpha chains and 1 beta chain. The central body of the alpha chain homopolymer supports tentacles, each with the binding site for C4b at the end.

Uniprot	P04003
Gene Name	C4BPA
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:722
Unigene	Hs.1012

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SKU	Supplier No.	Size	Your price	Quantity
BHE13801746	E0761h	96T	$736		Add to Cart

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