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Home / Primary Antibodies / Polyclonal Antibodies

Zyxin antibody

SKU : BHA10809734

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Mfr.No.	FNab09764
Alternative Names	ESP2 ; HED2 ; ZYX ; zyxin ; Zyxin2
Background	Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin(ZYX) is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles.
Categories	Primary Antibodies
Cellular Localization	Cell Junction, Cytoplasm, cytoskeleton, Nucleus
Clonality	polyclonal
Description	Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin (ZYX) is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles.
Host	Rabbit
Immunogen	zyxin
Isotype	IgG
Molecular Weight	80 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	Cell junction, Cytoplasm, Cytoskeleton, Nucleus
Synonyms	ESP 2, HED 2, ZYX, zyxin, Zyxin 2

Uniprot	Q15942
Gene Id	7791
Research Area	Cell Division and Proliferation, Signal Transduction
Weight	80kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB

Description

ELISA ; WB

Dilution

WB	1:200-1:2000

Tested Application

WB: 1:200-1:2000

Manual	FNab09764.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809734	FNab09764	100ug	$280		Add to Cart

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