Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II(RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in(A + T)-rich DNA regions. May play a role in neuronal differentiation and is able to bind DNA and activate expression in vitro.
Categories
Primary Antibodies
Cellular Localization
Nucleus
Clonality
polyclonal
Description
Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions. May play a role in neuronal differentiation and is able to bind DNA and activate expression in vitro.
Host
Rabbit
Immunogen
zinc finger protein 326
Isotype
IgG
Molecular Weight
67 kDa
Reactivity
Human, Mouse
Regulatory
RUO
Subcellular Location
Nucleus
Synonyms
DJ871E2.1, FLJ20403, ZAN75, Zfp326, zinc finger protein 326, ZNF326
Uniprot
Q5BKZ1
Gene Id
284695
Research Area
Cell Division and Proliferation, Metabolism
Weight
67kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)