Transcription factor required for myelination of differentiated oligodendrocytes. Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state. In the developing central nervous system(CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle. Specifically binds to the 5'-TCAT-3' DNA sequence(By similarity). Has transcription repressor activity in vitro.
Categories
Primary Antibodies
Cellular Localization
Nucleus
Clonality
polyclonal
Description
Transcription factor required for myelination of differentiated oligodendrocytes. Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state. In the developing central nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle. Specifically binds to the 5'-TCAT-3' DNA sequence (By similarity). Has transcription repressor activity in vitro.
Host
Rabbit
Immunogen
zinc finger protein 24
Isotype
IgG
Molecular Weight
42 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Subcellular Location
Nucleus
Synonyms
KOX17, RSG A, Zfp191, Zinc finger protein 191, zinc finger protein 24, Zinc finger protein KOX17, ZNF191, ZNF24, ZSCAN3
Uniprot
P17028
Gene Id
7572
Research Area
Metabolism
Weight
42kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)