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Home / Primary Antibodies / Polyclonal Antibodies

ZGPAT antibody

SKU : BHA10809604

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Mfr.No.	FNab09634
Alternative Names	ZGPAT ; ZC3HDC9 ; ZC3H9 ; KIAA1847 ; GPATCH6
Background	Transcription repressor that specifically binds the 5'-GGAG(GA)A(GA)A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis. Isoform 4: Antagonizes the transcription repression by isoform 1 by competing for the binding of the NuRD complex. Does not bind DNA.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Transcription repressor that specifically binds the 5'- GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis. Isoform 4: Antagonizes the transcription repression by isoform 1 by competing for the binding of the NuRD complex. Does not bind DNA.
Host	Rabbit
Immunogen	zinc finger, CCCH-type with G patch domain
Isotype	IgG
Molecular Weight	57 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	ZGPAT, ZC3HDC9, ZC3H9, KIAA1847, GPATCH6

Antigen	ZGPAT
Uniprot	Q8N5A5
Gene Id	84619
Research Area	Metabolism
Weight	57kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB

Description

ELISA ; WB

Dilution

WB	1:500-1:5000

Tested Application

WB: 1:500-1:5000

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809604	FNab09634	100ug	$280		Add to Cart

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