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Home / Primary Antibodies / Polyclonal Antibodies

ZFYVE19 antibody

SKU : BHA10809599

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Mfr.No.	FNab09629
Alternative Names	FLJ14840 ; MPFYVE ; ZFYVE19
Background	Key regulator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Together with CHMP4C, required to retain abscission-competent VPS4(VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Deactivation of AURKB results in dephosphorylation of CHMP4C followed by its dissociation from ZFYVE19/ANCHR and VPS4 and subsequent abscission.
Categories	Primary Antibodies
Cellular Localization	Cytoplasm, cytoskeleton
Clonality	polyclonal
Description	Key regulator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Together with CHMP4C, required to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Deactivation of AURKB results in dephosphorylation of CHMP4C followed by its dissociation from ZFYVE19/ANCHR and VPS4 and subsequent abscission.
Host	Rabbit
Immunogen	zinc finger, FYVE domain containing 19
Isotype	IgG
Molecular Weight	52 kDa
Reactivity	Human
Regulatory	RUO
Subcellular Location	Cytoplasm, Cytoskeleton
Synonyms	FLJ14840, MPFYVE, ZFYVE19

Antigen	ZFYVE19
Uniprot	Q96K21
Gene Id	84936
Research Area	Metabolism
Weight	52kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC

Dilution

WB	1:1000-1:10000
IHC	1:20-1:200

Tested Application

WB: 1:1000-1:10000; IHC: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809599	FNab09629	100ug	$280		Add to Cart

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