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Home / Primary Antibodies / Polyclonal Antibodies

ZFP36L2 antibody

SKU : BHA10809595

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Mfr.No.	FNab09625
Alternative Names	BRF2 ; Butyrateresponsefactor2 ; EGFresponsefactor2 ; ERF2 ; ERF2 ; ProteinTIS11D ; RNF162C ; TIS11D ; ZFP36L2
Background	mRNA-binding protein that plays a key role in self-renewal of erythroid cells in response to glucocorticoids. Specifically binds to the AU-rich element(ARE) in the 3'-UTR of target mRNAs, promoting their deadenylation and degradation(PubMed:14981510). Specifically expressed in burst-forming unit-erythroid(BFU-E) progenitors in response to glucocorticoids and acts as a negative regulator of erythroid cell differentiation: promotes self-renewal of erythroid cells by binding mRNAs that are induced or highly expressed during terminal erythroid differentiation and promotes their degradation, preventing erythroid cell differentiation. Down-regulated during erythroid differentiation from the BFU-E stage, stabilizing mRNAs required for terminal differentiation(By similarity).
Categories	Primary Antibodies
Clonality	polyclonal
Description	mRNA-binding protein that plays a key role in self- renewal of erythroid cells in response to glucocorticoids. Specifically binds to the AU-rich element (ARE) in the 3'-UTR of target mRNAs, promoting their deadenylation and degradation (PubMed:14981510). Specifically expressed in burst-forming unit- erythroid (BFU-E) progenitors in response to glucocorticoids and acts as a negative regulator of erythroid cell differentiation: promotes self-renewal of erythroid cells by binding mRNAs that are induced or highly expressed during terminal erythroid differentiation and promotes their degradation, preventing erythroid cell differentiation. Down-regulated during erythroid differentiation from the BFU-E stage, stabilizing mRNAs required for terminal differentiation (By similarity).
Host	Rabbit
Immunogen	zinc finger protein 36, C3H type-like 2
Isotype	IgG
Molecular Weight	51 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	BRF2, Butyrate response factor 2, EGF response factor 2, ERF 2, ERF2, Protein TIS11D, RNF162C, TIS11D, ZFP36L2

Uniprot	P47974
Gene Id	678
Research Area	Signal Transduction, Metabolism
Weight	51kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB

Description

ELISA ; WB

Dilution

WB	1:200-1:2000

Tested Application

WB: 1:200-1:2000

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809595	FNab09625	100ug	$260		Add to Cart

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