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Home / Primary Antibodies / Polyclonal Antibodies

ZEB1 antibody

SKU : BHA10809590

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Mfr.No.	FNab09620
Alternative Names	AREB6 ; BZP ; DELTAEF1 ; deltaEF1 ; NegativeregulatorofIL2 ; NIL2A ; NIL2Azincfingerprotein ; NIL2A ; NIL2A ; TCF8
Background	Acts as a transcriptional repressor. Inhibits interleukin-2(IL-2) gene expression. Enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and on the cell type. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition(EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1. Positively regulates neuronal differentiation. Represses RCOR1 transcription activation during neurogenesis. Represses transcription by binding to the E box(5'-CANNTG-3'). Promotes tumorigenicity by repressing stemness-inhibiting microRNAs. The calculated molecular weight of ZEB1 is 124 kDa, but the post phosphorylation of protein is about 190-210 kDa. This is a rabbit polyclonal antibody raised against part of the full length of ZEB1 of human.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Acts as a transcriptional repressor. Inhibits interleukin-2 (IL-2) gene expression. Enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and on the cell type. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1. Positively regulates neuronal differentiation. Represses RCOR1 transcription activation during neurogenesis. Represses transcription by binding to the E box (5'-CANNTG-3'). Promotes tumorigenicity by repressing stemness-inhibiting microRNAs.
Host	Rabbit
Immunogen	zinc finger E-box binding homeobox 1
Isotype	IgG
Molecular Weight	210 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	AREB6, BZP, DELTA EF1, delta EF1,, Negative regulator of IL2, NIL 2 A, NIL 2 A zinc finger protein, NIL 2A, NIL2A, TCF 8, TCF8, Transcription factor 8, ZEB, ZEB1, ZFHEP, ZFHX1A

Antigen	ZEB1
Uniprot	P37275
Gene Id	6935
Research Area	Metabolism
Weight	124kDa,Observed 210kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IP

Description

ELISA ; WB ; IP

Dilution

WB	1:500-1:5000
IP	1:200-1:2000

Tested Application

WB: 1:500-1:5000; IP: 1:200-1:2000?IHC: 1:500-1:5000

Manual	FNab09620.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809590	FNab09620	100ug	$260		Add to Cart

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