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Home / Primary Antibodies / Polyclonal Antibodies

ZBTB7B antibody

SKU : BHA10809568

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Mfr.No.	FNab09598
Alternative Names	CKrox ; DKFZp686G01254 ; hcKrox ; THPOK ; ZBTB15 ; ZBTB7B ; Zfp67 ; ZFP67 ; Zincfingerprotein67homolog ; ZincfingerproteinThPOK ; ZNF857B
Background	Transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. Necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors(thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. Transcriptional repressor of the collagen COL1A1 and COL1A2 genes. May also function as a repressor of fibronectin and possibly other extracellular matrix genes(By similarity).
Categories	Primary Antibodies
Cellular Localization	Nucleus
Clonality	polyclonal
Description	Transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. Necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. Transcriptional repressor of the collagen COL1A1 and COL1A2 genes. May also function as a repressor of fibronectin and possibly other extracellular matrix genes (By similarity).
Host	Rabbit
Immunogen	zinc finger and BTB domain containing 7B
Isotype	IgG
Molecular Weight	58 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	Nucleus
Synonyms	C Krox, DKFZp686G01254, hcKrox, THPOK, ZBTB15, ZBTB7B, Zfp 67, ZFP67, Zinc finger protein 67 homolog, Zinc finger protein Th POK, ZNF857B

Uniprot	O15156
Gene Id	51043
Research Area	Metabolism
Weight	58kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IF, IP

Description

ELISA ; WB ; IF ; IP

Dilution

WB	1:200-1:2000
IF	1:10-1:100
IP	1:200-1:1000

Tested Application

WB: 1:200-1:2000; IF: 1:10-1:100; IP: 1:200-1:1000

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809568	FNab09598	100ug	$260		Add to Cart

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