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Home / Primary Antibodies / Polyclonal Antibodies

ZBTB38 antibody

SKU : BHA10809563

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Mfr.No.	FNab09593
Alternative Names	ZBTB38 ; FLJ31131 ; FLJ35036 ; CIBZ ; FLJ22332
Background	Transcriptional regulator with bimodal DNA-binding specificity. Binds with a higher affinity to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' but can also bind to E-box elements(5'-CACGTG-3'). Can also bind specifically to a single methyl-CpG pair. Represses transcription in a methyl-CpG-dependent manner(PubMed:16354688). Plays an important role in regulating DNA replication and common fragile sites(CFS) stability in a RBBP6-and MCM10-dependent manner; represses expression of MCM10 which plays an important role in DNA-replication(PubMed:24726359). Acts as a transcriptional activator. May be involved in the differentiation and/or survival of late postmitotic neurons(By similarity).
Categories	Primary Antibodies
Cellular Localization	Chromosome, Nucleus
Clonality	polyclonal
Description	Transcriptional regulator with bimodal DNA-binding specificity. Binds with a higher affinity to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' but can also bind to E-box elements (5'-CACGTG-3'). Can also bind specifically to a single methyl-CpG pair. Represses transcription in a methyl- CpG-dependent manner (PubMed:16354688). Plays an important role in regulating DNA replication and common fragile sites (CFS) stability in a RBBP6- and MCM10-dependent manner; represses expression of MCM10 which plays an important role in DNA- replication (PubMed:24726359). Acts as a transcriptional activator. May be involved in the differentiation and/or survival of late postmitotic neurons (By similarity).
Host	Rabbit
Immunogen	zinc finger and BTB domain containing 38
Isotype	IgG
Molecular Weight	134 kDa
Reactivity	Human
Regulatory	RUO
Subcellular Location	Chromosome, Nucleus
Synonyms	ZBTB38, FLJ31131, FLJ35036, CIBZ, FLJ22332

Uniprot	Q8NAP3
Gene Id	253461
Research Area	Metabolism
Weight	134kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC

Dilution

WB	1:500-1:5000
IHC	1:20-1:200

Tested Application

WB: 1:500-1:5000; IHC: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809563	FNab09593	100ug	$280		Add to Cart

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