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Home / Primary Antibodies / Polyclonal Antibodies

ZBP1 antibody

SKU : BHA10809556

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Mfr.No.	FNab09586
Alternative Names	ZBP1 ; C20orf183 ; DLM1 ; ZDNAbindingprotein1 ; DLM1
Background	Participates in the detection by the host's innate immune system of DNA from viral, bacterial or even host origin. Plays a role in host defense against tumors and pathogens. Acts as a cytoplasmic DNA sensor which, when activated, induces the recruitment of TBK1 and IRF3 to its C-terminal region and activates the downstream interferon regulatory factor(IRF) and NF-kappa B transcription factors, leading to type-I interferon production. ZBP1-induced NF-kappaB activation probably involves the recruitment of the RHIM containing kinases RIPK1 and RIPK3(By similarity).
Categories	Primary Antibodies
Cellular Localization	Nucleus, Ytoplasm
Clonality	polyclonal
Description	Participates in the detection by the host's innate immune system of DNA from viral, bacterial or even host origin. Plays a role in host defense against tumors and pathogens. Acts as a cytoplasmic DNA sensor which, when activated, induces the recruitment of TBK1 and IRF3 to its C-terminal region and activates the downstream interferon regulatory factor (IRF) and NF-kappa B transcription factors, leading to type-I interferon production. ZBP1-induced NF-kappaB activation probably involves the recruitment of the RHIM containing kinases RIPK1 and RIPK3 (By similarity).
Host	Rabbit
Immunogen	Z-DNA binding protein 1
Isotype	IgG
Molecular Weight	66 kDa
Reactivity	Human
Regulatory	RUO
Subcellular Location	Nucleus,cytoplasm
Synonyms	ZBP1, C20orf183, DLM1, Z DNA binding protein 1, DLM 1

Uniprot	Q9H171
Gene Id	81030
Weight	49kDa,Observed 66kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC

Dilution

WB	1:500-1:5000
IHC	1:20-1:200

Tested Application

WB: 1:500-1:5000; IHC: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809556	FNab09586	100ug	$280		Add to Cart

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