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Home / Primary Antibodies / Polyclonal Antibodies

YOD1 antibody

SKU : BHA10809538

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Mfr.No.	FNab09567
Alternative Names	DKFZp451J1719 ; DUBA8 ; DUBA8 ; HIN7 ; HIN7 ; HIV1inducedprotease7 ; HsHIN7 ; OTUD2 ; PRO0907 ; UbiquitinthioesteraseOTU1 ; YOD1
Background	Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation(ERAD) for misfolded lumenal proteins. May act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore. Ubiquitin moieties on substrates may present a steric impediment to the threading process when the substrate is transferred to the VCP pore and threaded through VCP's axial channel. Mediates deubiquitination of 'Lys-27'-, 'Lys-29'-and 'Lys-33'-linked polyubiquitin chains. Also able to hydrolyze 'Lys-11'-linked ubiquitin chains. Cleaves both polyubiquitin and di-ubiquitin.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore. Ubiquitin moieties on substrates may present a steric impediment to the threading process when the substrate is transferred to the VCP pore and threaded through VCP's axial channel. Mediates deubiquitination of 'Lys-27'-, 'Lys-29'- and 'Lys-33'-linked polyubiquitin chains. Also able to hydrolyze 'Lys-11'-linked ubiquitin chains. Cleaves both polyubiquitin and di-ubiquitin.
Host	Rabbit
Immunogen	YOD1 OTU deubiquinating enzyme 1 homolog
Isotype	IgG
Molecular Weight	38 kDa
Reactivity	Human
Regulatory	RUO
Synonyms	DKFZp451J1719, DUBA 8, DUBA8, HIN 7, HIN7, HIV 1 induced protease 7, HsHIN7, OTUD2, PRO0907, Ubiquitin thioesterase OTU1, YOD1

Uniprot	Q5VVQ6
Gene Id	55432
Research Area	Epigenetics, Immunology, Metabolism
Weight	38kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB

Description

ELISA ; WB

Dilution

WB	1:500-1:5000

Tested Application

WB: 1:500-1:5000

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809538	FNab09567	100ug	$280		Add to Cart

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