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Home / Primary Antibodies / Polyclonal Antibodies

XRN1 antibody

SKU : BHA10809527

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Mfr.No.	FNab09556
Alternative Names	53exoribonuclease1 ; 5'3'exoribonuclease1 ; DKFZp434P0721 ; DKFZp686B22225 ; DKFZp686F19113 ; FLJ41903 ; 43344 ; XRN1
Background	Major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA(By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma(OGS).
Categories	Primary Antibodies
Cellular Localization	Cytoplasm
Clonality	polyclonal
Description	Major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS).
Host	Rabbit
Immunogen	5'-3' exoribonuclease 1
Isotype	IgG
Molecular Weight	192 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Subcellular Location	Cytoplasm
Synonyms	5 3 exoribonuclease 1, 5' 3' exoribonuclease 1, DKFZp434P0721, DKFZp686B22225, DKFZp686F19113, FLJ41903, SEP1, XRN1

Uniprot	Q8IZH2
Gene Id	54464
Research Area	Metabolism
Weight	192kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC, IF

Description

ELISA ; WB ; IHC ; IF

Dilution

WB	1:200-1:2000
IHC	1:20-1:200
IF	1:20-1:200

Tested Application

WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809527	FNab09556	100ug	$260		Add to Cart

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