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Home / Primary Antibodies / Polyclonal Antibodies

WWP1 antibody

SKU : BHA10809507

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Mfr.No.	FNab09534
Alternative Names	AIP5 ; DKFZp434D2111 ; hSDRP1 ; Tiul1 ; WWdomaincontainingprotein1 ; WWP1
Background	E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Ubiquitinates ERBB4 isoforms JM-A CYT-1 and JM-B CYT-1, KLF2, KLF5 and TP63 and promotes their proteasomal degradation. Ubiquitinates RNF11 without targeting it for degradation. Ubiquitinates and promotes degradation of TGFBR1; the ubiquitination is enhanced by SMAD7. Ubiquitinates SMAD6 and SMAD7. Ubiquitinates and promotes degradation of SMAD2 in response to TGF-beta signaling, which requires interaction with TGIF.
Categories	Primary Antibodies
Cellular Localization	Cytoplasm, Membrane, Nucleus
Clonality	polyclonal
Description	E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Ubiquitinates ERBB4 isoforms JM-A CYT-1 and JM-B CYT-1, KLF2, KLF5 and TP63 and promotes their proteasomal degradation. Ubiquitinates RNF11 without targeting it for degradation. Ubiquitinates and promotes degradation of TGFBR1; the ubiquitination is enhanced by SMAD7. Ubiquitinates SMAD6 and SMAD7. Ubiquitinates and promotes degradation of SMAD2 in response to TGF-beta signaling, which requires interaction with TGIF.
Host	Rabbit
Immunogen	WW domain containing E3 ubiquitin protein ligase 1
Isotype	IgG
Molecular Weight	90-110 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	Cell membrane, Cytoplasm, Membrane, Nucleus
Synonyms	AIP5, DKFZp434D2111, hSDRP1, Tiul1, WW domain containing protein 1, WWP1

Uniprot	Q9H0M0
Gene Id	11059
Research Area	Epigenetics, Signal Transduction, Metabolism
Weight	95kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IP

Description

ELISA ; WB ; IP

Dilution

WB	1:200-1:2000
IP	1:200-1:1000
IF	1:20-1:200

Tested Application

WB: 1:200-1:2000; IP: 1:200-1:1000; IF: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809507	FNab09534	100ug	$260		Add to Cart

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