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Home / Primary Antibodies / Polyclonal Antibodies

WISP1 antibody

SKU : BHA10809488

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Mfr.No.	FNab09514
Alternative Names	CCNfamilymember4 ; CCN4 ; WISP1 ; WISP1 ; WISP1c ; WISP1i ; WISP1tc ; Wnt1inducedsecretedprotein
Background	Downstream regulator in the Wnt/Frizzled-signaling pathway. Associated with cell survival. Attenuates p53-mediated apoptosis in response to DNA damage through activation of AKT kinase. Up-regulates the anti-apoptotic Bcl-X(L) protein. Adheres to skin and melanoma fibroblasts. In vitro binding to skin fibroblasts occurs through the proteoglycans, decorin and biglycan.
Categories	Primary Antibodies
Cellular Localization	Secreted
Clonality	polyclonal
Description	Downstream regulator in the Wnt/Frizzled-signaling pathway. Associated with cell survival. Attenuates p53-mediated apoptosis in response to DNA damage through activation of AKT kinase. Up-regulates the anti-apoptotic Bcl-X(L) protein. Adheres to skin and melanoma fibroblasts. In vitro binding to skin fibroblasts occurs through the proteoglycans, decorin and biglycan.
Host	Rabbit
Immunogen	WNT1 inducible signaling pathway protein 1
Isotype	IgG
Molecular Weight	45 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Subcellular Location	Secreted
Synonyms	CCN family member 4, CCN4, WISP 1, WISP1, WISP1c, WISP1i, WISP1tc, Wnt 1 induced secreted protein

Uniprot	O95388
Gene Id	8840
Research Area	Immunology, Cancer, Stem Cells
Weight	40kDa,Observed 45kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, IHC, IP, WB

Description

ELISA ; IHC ; IP ; WB

Dilution

WB	1:200-1:2000
IHC	1:20-1:200
IP	1:200-1:2000

Tested Application

WB: 1:200-1:2000; IHC: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809488	FNab09514	100ug	$260		Add to Cart

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